Center for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, CH-1015 Lausanne, Switzerland.
Center for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, CH-1015 Lausanne, Switzerland; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University Mainz, Staudingerweg 5, 55128 Mainz, Germany.
Mol Cell. 2024 May 2;84(9):1631-1632. doi: 10.1016/j.molcel.2024.04.005.
In this issue of Molecular Cell, Hao et al. demonstrate that the RNA helicase DDX21 recruits the mA methyltransferase complex to R-loops, ensuring proper transcription termination and genome stability.
在本期《分子细胞》中,郝等人证明 RNA 解旋酶 DDX21 将 mA 甲基转移酶复合物招募到 R 环上,确保了正确的转录终止和基因组稳定性。