Department of Neurosurgery, Mayo Clinic Arizona, Phoenix, AZ, USA.
Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Geroscience. 2024 Oct;46(5):5287-5301. doi: 10.1007/s11357-024-01171-7. Epub 2024 May 4.
Surgical management paradigms of spinal pathologies in the aging population carry inherent substantial risks, with surgical complications being more prevalent among patients with osteoporosis compared to those with normal bone mineral density. In this narrative review, we aim to highlight important clinical understanding and considerations in perioperative evaluation and management of patients elected to undergo spinal surgery. Osteoporosis is a well-defined risk factor for mechanical complications following spinal surgery, and as such, perioperative optimization of bone health in the setting of surgery for geriatric patients remains a critical research area alongside intraoperative surgical augmentation techniques. Surgical techniques to circumvent challenges with instrumentation of poor bone mineral density have included augmentation of pedicle screw fixation, including segmental bicortical screw fixation techniques, cement augmentation with fenestrated screws, or use of expandable pedicle screws to improve bone-implant interface. Judicious selection of treatment modalities and subsequent perioperative optimization is paramount to minimize surgical complications. Contemporary guidelines and evolving paradigms in perioperative evaluation, optimization, and management of the aging spine include the advent of quantitatively evaluating computed tomography (CT) via assessment of the magnitude of Hounsfield units. Prescribing pharmacotherapeutic agents and monitoring bone health requires a multidisciplinary team approach, including endocrinologists and geriatricians to coordinate high-quality care for advanced-age patients who require surgical management of their spinal disorders.
在老年人群中,脊柱病变的手术治疗模式存在固有风险,骨质疏松症患者的手术并发症比正常骨密度患者更为常见。在这篇叙述性综述中,我们旨在强调在选择接受脊柱手术的患者的围手术期评估和管理中需要重要的临床理解和考虑。骨质疏松症是脊柱手术后机械性并发症的明确危险因素,因此,老年患者手术时优化骨骼健康仍然是一个关键的研究领域,同时还需要研究术中手术增强技术。为了规避骨密度不佳的器械应用挑战而采用的手术技术包括增加椎弓根螺钉固定,包括节段性皮质骨螺钉固定技术、带孔螺钉的骨水泥增强,或使用可扩张椎弓根螺钉来改善骨-植入物界面。明智地选择治疗方式并进行后续的围手术期优化对于最大限度地减少手术并发症至关重要。老年脊柱的围手术期评估、优化和管理的当代指南和不断发展的模式包括通过评估亨氏单位的幅度来定量评估计算机断层扫描(CT)。为了为需要手术治疗脊柱疾病的高龄患者提供高质量的护理,需要内分泌学家和老年病学家等多学科团队来开处药物治疗并监测骨骼健康。