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术前CT衰减值分类评估112例OLIF手术病例中椎间融合器下沉风险。

Preoperative CT attenuation value classification assesses cage subsidence risk in 112 OLIF surgery cases.

作者信息

Chen Wanyan, Zhu Guangye, Song Zefeng, Chen Xingda, Tan Riwei, Liang Guibo, Zhou Zelin, Jiang Rueishiuan, Ren Hui, Liang De, Tang Jingjing, Jiang Xiaobing

机构信息

First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.

Department of Orthopaedic Surgery, Suzhou TCM Hospital, Nanjing University of Chinese Medicine, Suzhou, 215007, China.

出版信息

Sci Rep. 2025 Mar 25;15(1):10276. doi: 10.1038/s41598-025-94696-6.

DOI:10.1038/s41598-025-94696-6
PMID:40133602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11937231/
Abstract

Retrospective Study. This study investigates the effectiveness of preoperative vertebral computed tomography (CT) attenuation value classification in predicting cage subsidence in Oblique lumbar interbody fusion (OLIF) surgeries. This study aims to evaluate the feasibility of using CT attenuation value classification to predict cage subsidence. A retrospective analysis of L4-5 OLIF surgeries from May 2019 to June 2022, with over one year of follow-ups, was performed. Patients were classified into subsidence and non-subsidence groups based on postoperative outcomes. Demographic and perioperative variables, preoperative CT attenuation values, and changes in Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) scores were compared. Of 112 patients (29 in the subsidence group, 83 in the non-subsidence group), significant differences in gender (P = 0.032) and DXA T-value (P = 0.010) were noted, with the subsidence group predominantly female. The consistency of CT attenuation values across L1-L5 vertebral bodies demonstrated strong reliability, with intraclass correlation coefficient (ICC) ranging from 0.76 to 0.91. CT attenuation values, categorized into osteoporosis, osteopenia, and regular bone mass groups, correlated significantly with bone density and subsidence, especially at the L1 vertebra (r = 0.548, P < 0.001). Multivariate logistic regression confirmed the predictive value of vertebral CT stratification, with L1-L5 Odds Ratios (OR) ranging from 0.07 to 0.26. Females are more prone to OLIF-related cage subsidence. The measurement of CT attenuation values demonstrated strong reliability and consistency. Preoperative vertebral CT attenuation value classification correlates with bone density and subsidence risk, particularly at the L1 vertebra, and strongly predicts cage subsidence.

摘要

回顾性研究。本研究调查术前椎体计算机断层扫描(CT)衰减值分类在预测斜外侧腰椎椎间融合术(OLIF)中椎间融合器下沉方面的有效性。本研究旨在评估使用CT衰减值分类预测椎间融合器下沉的可行性。对2019年5月至2022年6月期间行L4 - 5 OLIF手术且随访超过一年的患者进行了回顾性分析。根据术后结果将患者分为下沉组和非下沉组。比较了人口统计学和围手术期变量、术前CT衰减值以及Oswestry功能障碍指数(ODI)和视觉模拟评分(VAS)的变化。在112例患者中(下沉组29例,非下沉组83例),发现性别(P = 0.032)和双能X线吸收法(DXA)T值(P = 0.010)存在显著差异,下沉组以女性为主。L1 - L5椎体CT衰减值的一致性显示出很强的可靠性,组内相关系数(ICC)范围为0.76至0.91。CT衰减值分为骨质疏松、骨质减少和正常骨量组,与骨密度和下沉显著相关,尤其是在L1椎体(r = 0.548,P < 0.001)。多因素逻辑回归证实了椎体CT分层的预测价值,L1 - L5的优势比(OR)范围为0.07至0.26。女性更容易发生与OLIF相关的椎间融合器下沉。CT衰减值的测量显示出很强的可靠性和一致性。术前椎体CT衰减值分类与骨密度及下沉风险相关,特别是在L1椎体,并能强烈预测椎间融合器下沉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/3759d3d367a3/41598_2025_94696_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/ea4948519ba8/41598_2025_94696_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/a8cbcae6b3f9/41598_2025_94696_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/38617231c8b3/41598_2025_94696_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/3759d3d367a3/41598_2025_94696_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/ea4948519ba8/41598_2025_94696_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/a8cbcae6b3f9/41598_2025_94696_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/38617231c8b3/41598_2025_94696_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb20/11937231/3759d3d367a3/41598_2025_94696_Fig3_HTML.jpg

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本文引用的文献

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Does Bone Density Affect Outcomes in Lateral Lumbar Interbody Fusion? A Propensity Score-Matched Analysis of Preoperative Hounsfield Units.骨密度会影响腰椎侧方椎间融合术的预后吗?术前亨氏单位的倾向评分匹配分析
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