Weill Cornell Medical College, New York, New York.
Department of Dermatology, The Warren Alpert Medical School at Brown University, Providence, Rhode Island.
J Am Acad Dermatol. 2024 Sep;91(3):480-489. doi: 10.1016/j.jaad.2024.04.032. Epub 2024 May 3.
Longitudinal erythronychia (LE) is defined as a longitudinal red band of the nail(s) and is classified as localized (involvement of 1 nail) or polydactylous (involvement of more than 1 nail). The differential diagnosis is distinct for these classifications. The etiologies of localized longitudinal erythronychia are most frequently benign subungual neoplasms and less often malignancies. Polydactylous longitudinal erythronychia is typically secondary to regional or systemic diseases, including lichen planus and Darier disease. LE is a common but underrecognized clinical finding. Increased dermatologist awareness of the clinical characteristics and differential diagnosis for LE is necessary given the possibility for malignancy and associated systemic disease. In this clinical review, the clinical features, differential diagnosis, evaluation, and management of LE are described.
纵向红甲(LE)是指指甲(甲)上出现的纵向红色条带,可分为局限性(累及 1 个指甲)或多甲性(累及多个指甲)。这两种分类的鉴别诊断是不同的。局限性纵向红甲的病因多为良性甲下肿瘤,恶性肿瘤较少见。多甲性纵向红甲通常继发于局部或全身疾病,包括扁平苔藓和 Darier 病。LE 是一种常见但未被充分认识的临床发现。鉴于 LE 可能存在恶性肿瘤和相关系统性疾病,提高皮肤科医生对其临床特征和鉴别诊断的认识是必要的。在本次临床综述中,描述了 LE 的临床特征、鉴别诊断、评估和管理。