全球及美国早产儿负担概述。
Overview of the Global and US Burden of Preterm Birth.
机构信息
Department of Pediatrics, Stanford University School of Medicine, 291 Campus Drive, Li Ka Shing Building, Stanford, CA 94305, USA.
Department of Pediatrics, Global Advancement of Infants and Mothers, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.
出版信息
Clin Perinatol. 2024 Jun;51(2):301-311. doi: 10.1016/j.clp.2024.02.015. Epub 2024 Apr 4.
Preterm birth (PTB) is the leading cause of morbidity and mortality in children globally, yet its prevalence has been difficult to accurately estimate due to unreliable methods of gestational age dating, heterogeneity in counting, and insufficient data. The estimated global PTB rate in 2020 was 9.9% (95% confidence interval: 9.1, 11.2), which reflects no significant change from 2010, and 81% of prematurity-related deaths occurred in Africa and Asia. PTB prevalence in the United States in 2021 was 10.5%, yet with concerning racial disparities. Few effective solutions for prematurity prevention have been identified, highlighting the importance of further research.
早产（PTB）是全球儿童发病和死亡的主要原因，但由于妊娠年龄估计方法不可靠、计数存在异质性以及数据不足，其流行率难以准确估计。2020 年全球早产率估计为 9.9%（95%置信区间：9.1，11.2），与 2010 年相比没有显著变化，81%的与早产相关的死亡发生在非洲和亚洲。2021 年美国的早产患病率为 10.5%，但存在令人担忧的种族差异。目前已经确定了一些预防早产的有效方法，这凸显了进一步研究的重要性。
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