J Emerg Nurs. 2024 May;50(3):336-341. doi: 10.1016/j.jen.2024.02.002.
The number of anesthetic body procedures in the United States is rapidly increasing, with many being performed on an outpatient basis. These procedures are advertised as being safe, and many times the serious complications may not be discussed. Although local anesthetic systemic toxicity is a rare complication, it is associated with an increase in morbidity. The emergency department staff should be aware of the possibility of this rare complication, as well as the variety of resulting symptoms (from minor to severe), potential sequelae, and appropriate management for patients who have undergone an outpatient anesthetic body procedure. Multiple factors contribute to the development of local anesthetic systemic toxicity, resulting in life-threatening effects on the neurologic and cardiovascular systems. Also, the site of administration, along with the local anesthetic agent used, can impact the risk of the development of local anesthetic systemic toxicity. To minimize the risk and ensure the best possible outcome for these patients, emergency department staff must be highly aware of the mechanisms, risk factors, prevention, and management/treatment of local anesthetic systemic toxicity.
美国的麻醉身体程序数量正在迅速增加，其中许多是在门诊进行的。这些程序被宣传为安全的，很多时候严重的并发症可能没有被讨论。虽然局部麻醉全身毒性是一种罕见的并发症，但它与发病率的增加有关。急诊科工作人员应该意识到这种罕见并发症的可能性，以及由此产生的各种症状（从轻微到严重）、潜在的后遗症，以及对接受门诊麻醉身体程序的患者的适当治疗。多种因素导致局部麻醉全身毒性的发展，对神经系统和心血管系统产生危及生命的影响。此外，给药部位以及使用的局部麻醉剂也会影响局部麻醉全身毒性发展的风险。为了最大限度地降低风险，并确保这些患者获得最佳的治疗效果，急诊科工作人员必须高度了解局部麻醉全身毒性的机制、危险因素、预防和管理/治疗。
