Author Affiliation: Western Division, University of Nebraska Medical Center College of Nursing, Scottsbluff, NE, United States; and Emergency Medicine, Aligned Providers of Wyoming, Kimball, NE, United States.
Adv Emerg Nurs J. 2024;46(3):234-240. doi: 10.1097/TME.0000000000000529. Epub 2024 Aug 1.
The purpose of this case study on local anesthetic systemic toxicity (LAST), a potentially life-threatening complication of local anesthetic, is to ensure that emergency nurse practitioners (ENPs) are knowledgeable on this disease process. Local anesthetics are used frequently, often daily, by ENPs, as well as multiple other health care providers for various procedures. They should be knowledgeable of the steps to resuscitate a patient who may have severe LAST. This case study reviews the emergency management of LAST, including pharmacologic treatment, deviations from routine advanced resuscitative guidelines, and disposition of the patient upon successful resuscitation. Additionally, risk assessment and clinical manifestations will be discussed. After reviewing this case study, ENPs should be able to recognize the presentation of LAST and provide emergent management to reduce complications, comorbidities, and death.
本案例研究旨在探讨局部麻醉药全身毒性（LAST）这一潜在危及生命的局部麻醉并发症，以确保急诊护士从业者（ENP）对这一疾病过程有足够的了解。局部麻醉药在急诊护理中被广泛应用，ENP 以及其他许多医疗保健提供者在进行各种手术时都会经常使用。他们应该了解如何对可能患有严重 LAST 的患者进行复苏。本案例研究回顾了 LAST 的紧急管理，包括药物治疗、对常规高级复苏指南的偏离以及成功复苏后患者的处置。此外，还将讨论风险评估和临床表现。在回顾本案例研究后，ENP 应该能够识别 LAST 的表现，并提供紧急管理，以减少并发症、合并症和死亡。
