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体外循环期间颗粒细胞的激活——鼓泡式、膜式和中空纤维氧合器的比较

Activation of granular cells during extracorporeal circulation--comparison between bubble-, membrane and hollowfiber oxygenators.

作者信息

Moosdorf R, Mulch J, Höge R, Neuhof H, Hoffmann C

机构信息

Department for Cardiovascular Surgery, Justus-Liebig-University, Giessen, W.-Germany.

出版信息

Life Support Syst. 1985;3 Suppl 1:289-93.

PMID:3870581
Abstract

Summarizing our data we can say, that some hematologic disorders during extracorporeal circulation can be diminished by the use of new oxygenator types like the membrane and the Hollowfiber oxygenator. This correlates to the results of other research teams. In contrast to that the activation of the complement cascade is caused by the three systems in a similar way. Although we know, that the activation of the complement systems is only one of numerous reasons for postoperative pulmonary complications, we still must regard this as an important factor, so that the aim of further investigations should be to reduce complement activation during long term ECC.

摘要

总结我们的数据可以说,体外循环期间的一些血液学紊乱可以通过使用新型氧合器,如膜式和中空纤维氧合器来减轻。这与其他研究团队的结果相关。与此形成对比的是,补体级联反应的激活是由这三种系统以类似的方式引起的。尽管我们知道,补体系统的激活只是术后肺部并发症众多原因之一,但我们仍必须将其视为一个重要因素,因此进一步研究的目标应该是在长期体外循环期间减少补体激活。

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Life Support Syst. 1985;3 Suppl 1:289-93.
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