University of Florida, Gainesville, USA.
Medical University of South Carolina, Charleston, USA.
J Perinatol. 2024 Sep;44(9):1312-1319. doi: 10.1038/s41372-024-01975-7. Epub 2024 May 6.
Infrequent breast pumping limits mother's own milk production in mothers of infants admitted to the neonatal intensive care unit. We aimed to determine the feasibility and benefit of biomarker-based personalized text messages on pumping frequency and milk sodium levels. A secondary aim examined lactation outcomes.
In this randomized controlled pilot study, 51 mothers were randomized to receive personalized text messages regarding pumping frequency or standard care.
There were no differences in pumped milk volume or sodium level, however, there was a trend towards the intervention group pumping more frequently, which was significant on day 5 (p = 0.035), and they lactated nearly 9 days longer. Post-hoc analysis found the intervention group tended to be more likely to pump ≥ 500 mL by day14 (p = 0.08), a marker of long-term lactation success.
Personalized biomarker-based text messages are feasible and may support lactation in mothers of critically ill infants.
新生儿重症监护病房（NICU）中婴儿的母亲如果不经常泵奶，会限制其自身的乳汁分泌。我们旨在确定基于生物标志物的个性化短信对泵奶频率和奶钠水平的可行性和益处。次要目标是研究哺乳结果。
在这项随机对照试验中，51 位母亲被随机分配接受关于泵奶频率的个性化短信或标准护理。
两组的泵奶量或奶钠水平没有差异，但干预组有更频繁泵奶的趋势，在第 5 天（p=0.035）差异显著，并且她们的哺乳期延长了近 9 天。事后分析发现，干预组在第 14 天更有可能泵出≥500ml（p=0.08），这是长期哺乳成功的标志。
基于生物标志物的个性化短信是可行的，可能有助于危重症婴儿的母亲进行哺乳。
