Division of Epidemiology and Biostatistics, Department of Public Health, Injibara University, Injibara, Ethiopia.
Division of Social Pharmacy, Department of Pharmacy, Injibara University, Injibara, Ethiopia.
Front Public Health. 2024 Apr 19;12:1258647. doi: 10.3389/fpubh.2024.1258647. eCollection 2024.
Severe acute malnutrition is a threat to child survival as mortality rates in children with severe malnutrition are nine times higher. Globally, about 19 million children are severely malnourished. This study looked at children aged 6-59 months admitted to hospital to see how quickly they recovered from severe acute malnutrition as well as what factors predicted their recovery.
The study included 543 systematically chosen children with severe acute malnutrition who were admitted to the stabilization center of a hospital. Data from the patient registry were gathered using a retrospective follow-up study design. In order to find predictors of recovery, the Cox proportional hazard model was applied.
From 543 children, 425 (78.27%) were recovered. The median survival time was 8 days. Having grade II edema, grade III edema, and pneumonia were negatively associated with recovery. Similarly, taking ceftriaxone, cloxacillin, and being on a nasogastric tube were associated with poor recovery. Conversely, better recovery rates were linked to exclusive breastfeeding and vitamin A supplementation.
Both the recovery rate and the median survival time fell within acceptable bounds. To boost the recovery rate, efforts are needed to lessen comorbidities.
严重急性营养不良对儿童生存构成威胁，因为严重营养不良儿童的死亡率要高出九倍。全球约有 1900 万儿童患有严重营养不良。本研究观察了住院的 6-59 个月大的儿童，以了解他们从严重急性营养不良中恢复的速度，以及哪些因素预测了他们的恢复情况。
该研究纳入了 543 名经系统选择的患有严重急性营养不良的儿童，他们被收入医院的稳定中心。使用回顾性随访研究设计，从患者登记处收集数据。为了寻找恢复的预测因素，应用了 Cox 比例风险模型。
在 543 名儿童中，425 名（78.27%）得到了恢复。中位生存时间为 8 天。存在 II 级水肿、III 级水肿和肺炎与恢复不良呈负相关。同样，使用头孢曲松、氯唑西林和鼻胃管与恢复不良有关。相反，纯母乳喂养和补充维生素 A 与更高的恢复率相关。
恢复率和中位生存时间均在可接受范围内。为了提高恢复率，需要努力减轻合并症。
