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中国河南省非结核分枝杆菌的流行情况及稀有菌种的出现。

Prevalence of nontuberculous mycobacteria and the emergence of rare species in Henan Province, China.

机构信息

Clinical Laboratory, Tuberculosis Department, Henan Chest Hospital, Zhengzhou, China.

出版信息

Epidemiol Infect. 2024 May 6;152:e92. doi: 10.1017/S095026882400061X.

Abstract

Nontuberculous mycobacteria (NTM) is a large group of mycobacteria other than the complex and Epidemiological investigations have found that the incidence of NTM infections is increasing in China, and it is naturally resistant to many antibiotics. Therefore, studies of NTM species in clinical isolates are useful for understanding the epidemiology of NTM infections. The present study aimed to investigate the incidence of NTM infections and types of NTM species. Of the 420 samples collected, 285 were positive for , 62 samples were negative, and the remaining 73 samples contained NTM, including 35 (8.3%) only NTM and 38 (9%) mixed ( and NTM). The most prevalent NTM species were (30.1%), followed by (15%) and (12%). infection was detected in 9.5% of total NTM-positive cases. Moreover, this study reports the presence of infection and a high prevalence of for the first time in Henan. is the most prevalent, accompanied by some emerging NTM species, including and a high prevalence of in Henan Province. Monitoring NTM transmission and epidemiology could enhance mycobacteriosis management in future.

摘要

非结核分枝杆菌(NTM)是一组除结核分枝杆菌复合体和麻风分枝杆菌以外的分枝杆菌。流行病学调查发现,我国 NTM 感染的发病率正在增加,且其对许多抗生素天然耐药。因此,对临床分离株中 NTM 种属的研究有助于了解 NTM 感染的流行病学。本研究旨在调查 NTM 感染的发生率和 NTM 种属类型。在采集的 420 份样本中,285 份为 阳性,62 份为阴性,其余 73 份含有 NTM,包括 35 份(8.3%)仅 NTM 和 38 份(9%)混合( 和 NTM)。最常见的 NTM 种属是 (30.1%),其次是 (15%)和 (12%)。在所有 NTM 阳性病例中,9.5%检测到 感染。此外,本研究首次在河南省报告了 感染的存在和 较高的流行率。是最常见的,同时存在一些新兴的 NTM 种属,包括 和河南省 较高的流行率。监测 NTM 的传播和流行病学有助于未来加强分枝杆菌病的管理。

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