活体动物中基底膜的动态变化：研究进展与潜在问题。
Basement membrane dynamics in living animals: Insights and pitfalls.
机构信息
Randall Centre for Cell and Molecular Biophysics, King's College London, London, UK.
Department of Biology, Duke University, Durham, NC, USA.
出版信息
J Cell Biol. 2024 Jul 1;223(7). doi: 10.1083/jcb.202402113. Epub 2024 May 6.
Abstract
Recent studies with fluorophore-tagged basement membrane (BM) components have led to remarkable discoveries about BMs but also inconsistent interpretations. Here, we review types of BM dynamics, discuss how we conduct and interpret fluorophore-tagged BM studies, and highlight experimental conditions that are important to consider.
摘要
最近使用荧光标记基底膜 (BM) 成分的研究导致了关于 BMs 的显著发现，但也存在不一致的解释。在这里，我们回顾了 BM 动力学的类型，讨论了我们如何进行和解释荧光标记 BM 研究，并强调了需要考虑的实验条件。
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