Alsaif Murtada, Farhat Ali, Blumer Zoe, Barham Leela
IPG Health Global Market Access, London, UK.
PharmaSaif Ltd, Slough, UK.
Health Econ Rev. 2024 May 6;14(1):32. doi: 10.1186/s13561-024-00505-7.
In 2022, updated guidance from NICE expanded the options for self-monitoring of blood glucose for patients with type 2 diabetes (T2DM), to include continuous glucose monitoring (CGM). In this budget impact analysis, the cost impact of CGM was compared with traditional self-monitoring of blood glucose (SMBG) in adults with T2DM over 1 year from the commissioner perspective in England.
The NICE-eligible T2DM cohort was split into 4 subgroups to enable nuanced costing by insulin administration frequency: basal human insulin, premixed insulin, basal-bolus insulin and bolus insulin. The model's cost components comprised mild and severe hypoglycaemia (SH), diabetic ketoacidosis (DKA), consumables and healthcare resource utilisation in primary and secondary care.
The introduction of CGM is estimated to be cost additive by approximately £4.6 million in the basecase, driven by increased spending on the CGM device. Overall, healthcare activity was reduced by approximately 20,000 attendances, due to fewer SH and DKA episodes in the CGM arm. General Practitioner (GP) practice-based activity is expected to drop after the first year as patients requiring CGM training is reduced. The budget impact could be neutralised if the CGM sensor was discounted by 13.2% (£29.76 to £25.83).
CGM may result in increased spending in the NICE-eligible T2DM cohort but is expected to reduce demand on secondary care services and GP time. These findings may be of interest to local decision-makers who wish to resolve the COVID-19 backlog with transformational investment in primary care to reduce secondary care activity.
2022年,英国国家卫生与临床优化研究所(NICE)发布的更新指南扩大了2型糖尿病(T2DM)患者自我血糖监测的选择范围,将持续葡萄糖监测(CGM)纳入其中。在这项预算影响分析中,从英国英格兰地区专员的角度,比较了CGM与传统自我血糖监测(SMBG)对成年T2DM患者1年的成本影响。
符合NICE标准的T2DM队列被分为4个亚组,以便根据胰岛素给药频率进行细致的成本核算:基础人胰岛素、预混胰岛素、基础-餐时胰岛素和餐时胰岛素。该模型的成本组成部分包括轻度和重度低血糖(SH)、糖尿病酮症酸中毒(DKA)、耗材以及初级和二级医疗保健中的医疗资源利用。
在基础案例中,引入CGM估计会使成本增加约460万英镑,这主要是由于CGM设备支出增加。总体而言,由于CGM组的SH和DKA发作次数减少,医疗保健活动减少了约20000人次。随着需要CGM培训的患者减少,预计第一年之后基于全科医生(GP)诊所的活动会下降。如果CGM传感器打13.2%的折扣(从29.76英镑降至25.83英镑),预算影响可能会抵消。
CGM可能会导致符合NICE标准的T2DM队列支出增加,但预计会减少对二级医疗服务和GP时间的需求。这些发现可能会引起当地决策者的兴趣,他们希望通过对初级医疗保健进行变革性投资来解决新冠疫情积压问题,以减少二级医疗保健活动。