Department of Surgery, Stanford University, Palo Alto, California.
Surg Infect (Larchmt). 2024 Jun;25(5):357-361. doi: 10.1089/sur.2024.070. Epub 2024 May 6.
species were first isolated in 1941. Since then, 48 cases of bacteremia have been reported, a majority of which were immunosuppressed patients with central venous catheters.A case is described and previous cases of bacteremia are reviewed. A 70-year-old total parenteral nutrition (TPN)-dependent female with recurrent enterocutaneous fistula (ECF), developed leukocytosis one week after a challenging ECF takedown. After starting broad-spectrum antibiotic agents, undergoing percutaneous drainage of intra-abdominal abscess, and subsequent repositioning of the drain, her leukocytosis resolved. Blood and peripherally inserted central catheter (PICC) cultures grew spp. The patient was discharged to home with 14 days of daily 2 g ceftriaxone, with resolution of bacteremia. spp. are a rare opportunistic pathogen predominantly affecting immunocompromised patients, with central venous catheters present in most cases. However, there have been few reported cases in immunocompetent individuals with predisposing conditions such as end-stage renal disease and uncontrolled diabetes mellitus.
种于 1941 年首次分离。自那时以来,已有 48 例菌血症报告,其中大多数是伴有中心静脉导管的免疫抑制患者。描述了 1 例病例并回顾了以前的菌血症病例。一名 70 岁的全胃肠外营养(TPN)依赖女性,因反复肠外瘘(ECF)而行 ECF 松解术 1 周后出现白细胞增多。在开始使用广谱抗生素、经皮引流腹腔脓肿和随后重新放置引流管后,她的白细胞增多症得到缓解。血液和外周插入中心导管(PICC)培养物中生长了 种。患者接受了 14 天的每日 2 g 头孢曲松治疗,菌血症得到了治愈。 种是一种罕见的机会性病原体,主要影响免疫功能低下的患者,大多数病例中存在中心静脉导管。然而,在免疫功能正常的个体中,也有一些有倾向的疾病,如终末期肾病和未控制的糖尿病的报道。