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[T细胞和B细胞对三种不同形式人乳头瘤病毒(HPV)疫苗接种反应差异的研究进展]

[Research progress on the differences between T and B cell responses to three different forms of human papilloma virus (HPV) vaccination].

作者信息

Peng Qi, Li Yangyang, Li Jun, Yao Xinsheng

机构信息

Department of Immunology, Zunyi Medical University, Zunyi 563000, China.

Department of Immunology, Zunyi Medical University, Zunyi 563000, China. *Corresponding author, E-mail:

出版信息

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2024 Apr;40(4):378-382.

Abstract

One of the most prevalent malignancies in women is cervical cancer. Cervical cancer is mostly brought on by chronic high-risk human papillomavirus 16 (HPV16) and HPV18 infection. Currently, the widely used HPV vaccines are the bivalent Cervarix, the tetravalent Gardasil, and the 9-valent Gardasil-9.There are differences in T cell effector molecule changes, B cell antibody level, duration, age and the injection after vaccination of the three vaccines.

摘要

宫颈癌是女性中最常见的恶性肿瘤之一。宫颈癌主要由慢性高危人乳头瘤病毒16型(HPV16)和HPV18感染引起。目前,广泛使用的HPV疫苗有二价的希瑞适、四价的佳达修和九价的佳达修9。这三种疫苗在T细胞效应分子变化、B细胞抗体水平、持续时间、适用年龄以及接种后的注射方面存在差异。

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