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利用疟疾疫苗和 mRNA 技术解决全球制药研发和生产中的不平等问题,以实现疾病消除。

Leveraging malaria vaccines and mRNA technology to tackle the global inequity in pharmaceutical research and production towards disease elimination.

机构信息

Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.

出版信息

Malar J. 2024 May 6;23(1):136. doi: 10.1186/s12936-024-04972-5.

Abstract

Malaria vaccine introduction in endemic countries is a game-changing milestone in the fight against the disease. This article examines the inequity in the global pharmaceutical research, development, manufacturing, and trade landscape. The role of inequity in hindering progress towards malaria elimination is explored. The analysis finds that transformational changes are required to create an equity-enabling environment. Addressing the inequity is critical to maximizing the public health impact of vaccines and attaining sustainability. Avenues to catalyze progress by leveraging malaria vaccines and messenger ribonucleic acid (mRNA) technology are discussed.

摘要

疟疾疫苗在流行国家的引入是对抗该疾病的一个具有变革意义的里程碑。本文探讨了在全球制药研发、制造和贸易格局中存在的不平等现象。分析发现,需要进行变革性的改变,以创造一个有利于公平的环境。解决不平等问题对于最大限度地发挥疫苗的公共卫生影响和实现可持续性至关重要。本文还讨论了利用疟疾疫苗和信使核糖核酸(mRNA)技术来推动进展的途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4b/11075248/30d7908ece10/12936_2024_4972_Fig1_HTML.jpg

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