Campbell S A, Dys S P, Henderson J M T, Bradley H A, Rucklidge J J
School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand.
Department of Psychology, Simon Fraser University, Burnaby, BC, Canada.
Front Nutr. 2024 Apr 22;11:1307701. doi: 10.3389/fnut.2024.1307701. eCollection 2024.
Antenatal depression and maternal nutrition can influence infant temperament. Although broad-spectrum-micronutrients (BSM: vitamins and minerals) given above Recommended Dietary Allowances during pregnancy can mitigate symptoms of antenatal depression, their associated effects on infant temperament are unknown. One hundred and fourteen New Zealand mother-infant dyads (45 infants exposed to BSM during pregnancy (range of exposure during pregnancy: 12-182 days) to treat antenatal depressive symptoms (measured by Edinburgh Postnatal Depression Scale) and 69 non-exposed infants) were followed antenatally and for 12 months postpartum to determine the influence of BSM exposure on infant temperament. The Infant Behavior Questionnaire-Revised: Very Short-Form assessed temperament at 4 (T1), 6 (T2) and 12 (T3) months postpartum via online questionnaire. Latent growth curve modeling showed BSM exposure, antenatal depression and infant sex did not statistically significantly predict initial levels or longitudinal changes in orienting/regulatory capacity (ORC), positive affectivity/surgency (PAS) or negative affectivity (NEG). Higher gestational age was positively associated with initial PAS, and smaller increases between T1 and T3. Breastfeeding occurrence was positively associated with initial NEG. Although not significant, BSM exposure exerted small, positive effects on initial NEG ( = -0.116) and longitudinal changes in ORC ( = 0.266) and NEG ( = -0.235). While BSM exposure did not significantly predict infant temperament, it may mitigate risks associated with antenatal depression. BSM-exposed infants displayed temperamental characteristics on par with typical pregnancies, supporting the safety of BSM treatment for antenatal depression.
产前抑郁和母体营养会影响婴儿气质。虽然孕期摄入超过推荐膳食摄入量的广谱微量营养素（BSM：维生素和矿物质）可减轻产前抑郁症状，但其对婴儿气质的相关影响尚不清楚。对114对新西兰母婴二元组（45名孕期暴露于BSM的婴儿（孕期暴露时间范围：12 - 182天）以治疗产前抑郁症状（通过爱丁堡产后抑郁量表测量）和69名未暴露婴儿）进行产前及产后12个月的跟踪，以确定BSM暴露对婴儿气质的影响。修订版婴儿行为问卷简版通过在线问卷在产后4个月（T1）、6个月（T2）和12个月（T3）评估气质。潜在生长曲线模型显示，BSM暴露、产前抑郁和婴儿性别在统计学上均未显著预测定向/调节能力（ORC）、积极情感/冲动性（PAS）或消极情感（NEG）的初始水平或纵向变化。较高的胎龄与初始PAS呈正相关，且T1至T3之间的增长较小。母乳喂养发生率与初始NEG呈正相关。虽然不显著，但BSM暴露对初始NEG（β = -0.116）、ORC的纵向变化（β = 0.266）和NEG的纵向变化（β = -0.235）产生了微小的积极影响。虽然BSM暴露未显著预测婴儿气质，但它可能减轻与产前抑郁相关的风险。暴露于BSM 的婴儿表现出与典型妊娠相当的气质特征，支持BSM治疗产前抑郁的安全性。
