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[休克时肝脏的超微结构病理学]

[Ultrastructural pathology of the liver in shock].

作者信息

Grimaud J A, Chevallier M

出版信息

Ann Anesthesiol Fr. 1979;20(2):95-103.

PMID:38714
Abstract

Ultrastructural findings in shock liver are in general very similar to data in the literature concerning experimental ischaemia in the animal. It is firstly a cellular disease which leads to a tissue disease, reflected morphologically by definitive and irreversible signs in the absence of hepatocellular regeneration. Assessment on the cellular scale of lesions of ischaemia may be used to define the potentially reversible nature of certain signs and should be adpated to the study of the cellular effects of therapeutic measures. By contrast, in practical terms it cannot be used for the quantitative assessment of the spatial extent of lesions within the hepatic acinus.

摘要

休克肝的超微结构发现总体上与文献中关于动物实验性缺血的数据非常相似。它首先是一种细胞疾病,进而导致组织疾病,在缺乏肝细胞再生的情况下,形态学上表现为明确且不可逆的征象。在细胞层面评估缺血性损伤可用于确定某些征象的潜在可逆性,并且应适用于研究治疗措施的细胞效应。相比之下,实际上它不能用于定量评估肝腺泡内病变的空间范围。

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