Kermarec J
Ann Anesthesiol Fr. 1979;20(2):89-94.
Microscopic lesions in shock liver, examined in biopsy specimens from 20 patients, are characterised by elective involvement of the hepatic parenchyma inthe peripheral zones of the acini, with necrosis and cell loss in approximately half the cases. The particular appearance of the degenerative lesions of the hepatocytes ("ischaemic atrophy" and tumefaction, monocellular necrosis), the absence of any change in the reticulin fibres, the minimal leucocytic reaction and the absence of any damage to the portal spaces should make it possible to identify histologically the ischaemic aetiology of peri-acinar hepatic lesions.
对20例患者的活检标本进行检查,发现休克肝的微观病变特征为肝实质选择性累及腺泡外周区,约半数病例出现坏死和细胞丢失。肝细胞变性病变的特殊表现(“缺血性萎缩”和肿胀、单细胞坏死)、网状纤维无任何变化、白细胞反应轻微以及门管区无任何损伤,应有助于从组织学上确定腺泡周围肝损伤的缺血病因。