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桥小脑角脑膜瘤:临床表现与诊断

Cerebellopontine angle meningiomas: clinical manifestations and diagnosis.

作者信息

Granick M S, Martuza R L, Parker S W, Ojemann R G, Montgomery W W

出版信息

Ann Otol Rhinol Laryngol. 1985 Jan-Feb;94(1 Pt 1):34-8. doi: 10.1177/000348948509400108.

DOI:10.1177/000348948509400108
PMID:3871599
Abstract

Cerebellopontine angle (CPA) meningiomas constitute about 1% of intracranial meningiomas. The clinical aspects of a series of 32 patients with surgically confirmed CPA meningiomas are analyzed. The most common symptoms at the time of the initial evaluation were from the eighth cranial nerve (unilateral hearing loss--24 patients, vertigo or imbalance--19 patients, tinnitus--11 patients), and the fifth cranial nerve (altered sensation--9 patients, facial pain--5 patients). On examination, the most common findings were absent caloric response (19 patients), nystagmus (16 patients), diminished facial sensation (14 patients), ataxia (13 patients), reduced hearing (9 patients), and facial weakness (9 patients). There was often a long interval from the onset of symptoms to the correct diagnosis of a tumor. Brain stem auditory evoked potentials, blink reflex testing, posterior fossa myelography, computerized tomographic scanning, and angiography were abnormal in all patients in whom the test was done, but all tests were not performed on all patients. Computerized tomographic scanning and angiography are important for definitive diagnosis and for planning surgical treatment. The histopathology of the temporal bone was studied in three patients with meningiomas in the region of the internal auditory meatus.

摘要

桥小脑角(CPA)脑膜瘤约占颅内脑膜瘤的1%。本文分析了32例经手术证实的CPA脑膜瘤患者的临床情况。初次评估时最常见的症状来自第八对脑神经(单侧听力丧失——24例患者,眩晕或平衡失调——19例患者,耳鸣——11例患者),以及第五对脑神经(感觉改变——9例患者,面部疼痛——5例患者)。检查时,最常见的体征是冷热反应消失(19例患者)、眼球震颤(16例患者)、面部感觉减退(14例患者)、共济失调(13例患者)、听力下降(9例患者)和面部无力(9例患者)。从症状出现到肿瘤确诊往往有很长的间隔时间。在所有接受检测的患者中,脑干听觉诱发电位、眨眼反射测试、后颅窝脊髓造影、计算机断层扫描和血管造影均异常,但并非所有患者都进行了所有检测。计算机断层扫描和血管造影对于明确诊断和规划手术治疗很重要。对3例内耳道区域脑膜瘤患者的颞骨组织病理学进行了研究。

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