Greenburg A G, Saik R P, Bell R H, Collins G M
Arch Surg. 1985 Mar;120(3):341-4. doi: 10.1001/archsurg.1985.01390270079013.
This study, a retrospective analysis of 351 patients with acute gastrointestinal (GI) hemorrhage, was undertaken to define patterns of disease and age-related operative and mortality rates and to determine changes over time related to changes in management. One third (116 patients) of the admissions had bleeding esophageal varices. Upper GI hemorrhage accounted for 85% (N = 200) and lower GI hemorrhage for 15% (N = 35). Emergency surgical intervention was required in 90 patients (38%), 40% of the upper and 29% of the lower GI hemorrhage patients. Benign ulcer disease accounted for 86% of the cases requiring emergency surgery and was treated with vagotomy and drainage and/or oversewing. Lower GI bleeding is seen in older patients; it has a lower operative intervention rate and a higher mortality. Stress bleeding as a surgical lesion has disappeared since 1979. A more assertive policy for surgical intervention has decreased operative mortality for all age groups. Bleeding duodenal ulcers are decreasing in incidence while gastric lesions appear to be increasing. These population-specific patterns, different from earlier periods, may have implications for training and patient management decisions.
本研究对351例急性胃肠道出血患者进行了回顾性分析,旨在明确疾病模式、与年龄相关的手术率和死亡率,并确定随时间推移与管理变化相关的改变。三分之一(116例患者)的入院患者患有食管静脉曲张出血。上消化道出血占85%(N = 200),下消化道出血占15%(N = 35)。90例患者(38%)需要进行急诊手术干预,其中上消化道出血患者的比例为40%,下消化道出血患者的比例为29%。良性溃疡病占需要急诊手术病例的86%,采用迷走神经切断术和引流及/或缝扎治疗。下消化道出血多见于老年患者;其手术干预率较低,死亡率较高。自1979年以来,应激性出血作为一种外科病变已消失。更积极的手术干预策略降低了所有年龄组的手术死亡率。十二指肠溃疡出血的发病率在下降,而胃部病变似乎在增加。这些特定人群的模式与早期不同,可能对培训和患者管理决策产生影响。