Checketts T Rees, Gautam Manjushree, Mudrovich Steven, Gonzalez Stevan A
Department of Medicine, Creighton University School of Medicine, Omaha, NE.
Baylor Simmons Transplant Institute, Baylor Scott & White All Saints Medical Center Fort Worth, TX.
ACG Case Rep J. 2024 May 6;11(5):e01358. doi: 10.14309/crj.0000000000001358. eCollection 2024 May.
Duodenal-type follicular lymphoma (DFL) are uncommon, presenting in both symptomatic and asymptomatic patients, and are generally associated with a benign clinical course. Treatment options include surgery, radiation, and chemotherapy. However, many patients can be managed conservatively with little to no treatment, as 5-year progression-free survival is greater than 70%, and 5-year overall survival ranges from 80% to 94%. Here, we present a case of incidental DFL in a patient with metabolic dysfunction-associated steatohepatitis and cirrhosis. A review of the endoscopic and histologic characteristics, as well as epidemiology, risk factors, and long-term outcomes, may guide management strategies when DFL is encountered.
十二指肠型滤泡性淋巴瘤(DFL)并不常见,可发生于有症状和无症状的患者,通常与良性临床病程相关。治疗选择包括手术、放疗和化疗。然而,许多患者可以采取保守治疗,几乎无需治疗,因为5年无进展生存率大于70%,5年总生存率在80%至94%之间。在此,我们报告一例代谢功能障碍相关脂肪性肝炎和肝硬化患者并发DFL的病例。对内镜和组织学特征以及流行病学、危险因素和长期结局进行回顾,可能有助于指导遇到DFL时的管理策略。