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代谢功能障碍相关脂肪性肝炎肝硬化中偶然发现十二指肠型滤泡性淋巴瘤:一种预后良好的罕见恶性肿瘤。

Incidental Finding of a Duodenal-Type Follicular Lymphoma in Metabolic Dysfunction-Associated Steatohepatitis Cirrhosis: A Rare Malignancy With Favorable Outcomes.

作者信息

Checketts T Rees, Gautam Manjushree, Mudrovich Steven, Gonzalez Stevan A

机构信息

Department of Medicine, Creighton University School of Medicine, Omaha, NE.

Baylor Simmons Transplant Institute, Baylor Scott & White All Saints Medical Center Fort Worth, TX.

出版信息

ACG Case Rep J. 2024 May 6;11(5):e01358. doi: 10.14309/crj.0000000000001358. eCollection 2024 May.

DOI:10.14309/crj.0000000000001358
PMID:38716359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11075945/
Abstract

Duodenal-type follicular lymphoma (DFL) are uncommon, presenting in both symptomatic and asymptomatic patients, and are generally associated with a benign clinical course. Treatment options include surgery, radiation, and chemotherapy. However, many patients can be managed conservatively with little to no treatment, as 5-year progression-free survival is greater than 70%, and 5-year overall survival ranges from 80% to 94%. Here, we present a case of incidental DFL in a patient with metabolic dysfunction-associated steatohepatitis and cirrhosis. A review of the endoscopic and histologic characteristics, as well as epidemiology, risk factors, and long-term outcomes, may guide management strategies when DFL is encountered.

摘要

十二指肠型滤泡性淋巴瘤(DFL)并不常见,可发生于有症状和无症状的患者,通常与良性临床病程相关。治疗选择包括手术、放疗和化疗。然而,许多患者可以采取保守治疗,几乎无需治疗,因为5年无进展生存率大于70%,5年总生存率在80%至94%之间。在此,我们报告一例代谢功能障碍相关脂肪性肝炎和肝硬化患者并发DFL的病例。对内镜和组织学特征以及流行病学、危险因素和长期结局进行回顾,可能有助于指导遇到DFL时的管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f6/11075945/e483673d12f5/ac9-11-e01358-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f6/11075945/d50beeff82b7/ac9-11-e01358-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f6/11075945/e483673d12f5/ac9-11-e01358-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f6/11075945/d50beeff82b7/ac9-11-e01358-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f6/11075945/e483673d12f5/ac9-11-e01358-g002.jpg

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Am J Surg Pathol. 2023 Oct 1;47(10):1134-1143. doi: 10.1097/PAS.0000000000002095. Epub 2023 Jul 27.
2
Duodenal-type follicular lymphoma more than 10 years after treatment intervention: A retrospective single-center analysis.治疗干预后10年以上的十二指肠型滤泡性淋巴瘤:一项回顾性单中心分析
World J Gastrointest Oncol. 2022 Aug 15;14(8):1552-1561. doi: 10.4251/wjgo.v14.i8.1552.
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Bacterial infection-driven lymphomagenesis.
细菌感染驱动的淋巴瘤发生。
Curr Opin Oncol. 2022 Sep 1;34(5):454-463. doi: 10.1097/CCO.0000000000000886. Epub 2022 Jul 25.
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Clinical features and outcomes of duodenal-type follicular lymphoma: A single-center retrospective study.十二指肠型滤泡性淋巴瘤的临床特征与预后:一项单中心回顾性研究
EJHaem. 2022 Jan 31;3(2):379-384. doi: 10.1002/jha2.384. eCollection 2022 May.
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Development of diffuse large B-cell lymphoma from duodenal type follicular lymphoma: a retrospective study of 23 cases.十二指肠型滤泡性淋巴瘤转化为弥漫性大B细胞淋巴瘤:23例回顾性研究
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