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急性静脉曲张出血后结局的预测。

Prediction of outcome following acute variceal haemorrhage.

作者信息

Garden O J, Motyl H, Gilmour W H, Utley R J, Carter D C

出版信息

Br J Surg. 1985 Feb;72(2):91-5. doi: 10.1002/bjs.1800720205.

DOI:10.1002/bjs.1800720205
PMID:3871650
Abstract

In order to identify factors predicting survival following acute variceal haemorrhage, data were collected prospectively from 100 admissions in 70 patients managed by a standard policy employing oesophageal tamponade, injection sclerotherapy and, if necessary, oesophageal transection. Of the ten predictive factors identified by univariate analysis, only prothrombin ratio, serum creatinine and the presence of encephalopathy on admission were shown by stepwise logistic regression to have independent significance. The derived regression equation allowed clearer identification than conventional scoring systems of high and low risk groups and successfully predicted outcome in 90 per cent of admissions.

摘要

为了确定预测急性静脉曲张出血后存活的因素,我们前瞻性地收集了70例患者100次住院的数据,这些患者采用标准治疗策略,包括食管压迫、注射硬化疗法,必要时进行食管横断术。在单因素分析确定的10个预测因素中,逐步逻辑回归显示只有凝血酶原比率、血清肌酐和入院时存在脑病具有独立意义。所推导的回归方程比传统评分系统能更清晰地识别高风险和低风险组,并成功预测了90%住院患者的结局。

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Prediction of outcome following acute variceal haemorrhage.急性静脉曲张出血后结局的预测。
Br J Surg. 1985 Feb;72(2):91-5. doi: 10.1002/bjs.1800720205.
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引用本文的文献

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Gastrointestinal Bleeding in Cirrhotic Patients with Portal Hypertension.门静脉高压肝硬化患者的胃肠道出血
ISRN Hepatol. 2013 Jul 22;2013:541836. doi: 10.1155/2013/541836. eCollection 2013.
2
Management of portal hypertensive gastropathy and other bleeding.门静脉高压性胃病和其他出血的处理。
Clin Mol Hepatol. 2014 Mar;20(1):1-5. doi: 10.3350/cmh.2014.20.1.1. Epub 2014 Mar 26.
3
Non-variceal gastrointestinal bleeding in patients with liver cirrhosis: a review.肝硬化患者的非静脉曲张性胃肠道出血:综述。
Dig Dis Sci. 2012 Nov;57(11):2743-54. doi: 10.1007/s10620-012-2229-x. Epub 2012 Jun 4.
4
Improved survival with the patients with variceal bleed.静脉曲张出血患者的生存率提高。
Int J Hepatol. 2011;2011:356919. doi: 10.4061/2011/356919. Epub 2011 Jul 7.
5
Antibiotic prophylaxis in variceal hemorrhage: timing, effectiveness and Clostridium difficile rates.预防性使用抗生素治疗静脉曲张出血:时机、疗效和艰难梭菌感染率。
World J Gastroenterol. 2010 Nov 14;16(42):5317-23. doi: 10.3748/wjg.v16.i42.5317.
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Predictive factors for rebleeding and death in alcoholic cirrhotic patients with acute variceal bleeding: a multivariate analysis.酒精性肝硬化急性静脉曲张出血患者再出血和死亡的预测因素:一项多变量分析。
World J Surg. 2009 Oct;33(10):2127-35. doi: 10.1007/s00268-009-0172-6.
7
A comparison of Child-Pugh, APACHE II and APACHE III scoring systems in predicting hospital mortality of patients with liver cirrhosis.Child-Pugh、APACHE II和APACHE III评分系统在预测肝硬化患者医院死亡率方面的比较。
BMC Gastroenterol. 2003 May 8;3:7. doi: 10.1186/1471-230X-3-7.
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Acute variceal bleeding: general management.急性静脉曲张出血:一般处理
World J Gastroenterol. 2001 Aug;7(4):466-75. doi: 10.3748/wjg.v7.i4.466.
9
UK guidelines on the management of variceal haemorrhage in cirrhotic patients. British Society of Gastroenterology.英国肝硬化患者静脉曲张出血管理指南。英国胃肠病学会。
Gut. 2000 Jun;46 Suppl 3-4(Suppl 3):III1-III15. doi: 10.1136/gut.46.suppl_3.iii1.
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World J Surg. 1994 Mar-Apr;18(2):176-84. doi: 10.1007/BF00294398.