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新型口腔伤口护理功能性敷料材料。

Novel Functional Dressing Materials for Intraoral Wound Care.

机构信息

State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.

出版信息

Adv Healthc Mater. 2024 Sep;13(23):e2400912. doi: 10.1002/adhm.202400912. Epub 2024 May 21.

Abstract

Intraoral wounds represent a particularly challenging category of mucosal and hard tissue injuries, characterized by the unique structures, complex environment, and distinctive healing processes within the oral cavity. They have a common occurrence yet frequently inflict significant inconvenience and pain on patients, causing a serious decline in the quality of life. A variety of novel functional dressings specifically designed for the moist and dynamic oral environment have been developed and realized accelerated and improved wound healing. Thoroughly analyzing and summarizing these materials is of paramount importance in enhancing the understanding and proficiently managing intraoral wounds. In this review, the particular processes and unique characteristics of intraoral wound healing are firstly described. Up-to-date knowledge of various forms, properties, and applications of existing products are then intensively discussed, which are categorized into animal products, plant extracts, natural polymers, and synthetic products. To conclude, this review presents a comprehensive framework of currently available functional intraoral wound dressings, with an aim to provoke inspiration of future studies to design more convenient and versatile materials.

摘要

口腔内伤口是一类具有挑战性的黏膜和硬组织损伤,其特点是口腔内具有独特的结构、复杂的环境和独特的愈合过程。它们很常见,但经常给患者带来很大的不便和疼痛,严重降低了生活质量。已经开发出了各种专门为湿润和动态口腔环境设计的新型功能性敷料,实现了伤口的加速愈合和改善。彻底分析和总结这些材料对于提高对口腔内伤口的理解和熟练处理至关重要。在这篇综述中,首先描述了口腔内伤口愈合的特殊过程和独特特征。然后,详细讨论了现有产品的各种形式、特性和应用的最新知识,这些产品分为动物产品、植物提取物、天然聚合物和合成产品。总之,本文综述了目前可用的功能性口腔内伤口敷料,旨在为未来设计更方便、多功能的材料提供灵感。

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