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弥合鸿沟：从普遍的种系基因检测指南到胰腺癌护理的实际实施。

Bridging the Divide: From Universal Germline Testing Guidance to Real-World Implementation in Pancreatic Cancer Care.

机构信息

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

Department of Medicine, Brigham and Women's Hospital, Boston, MA.

出版信息

JCO Oncol Pract. 2024 Aug;20(8):1012-1015. doi: 10.1200/OP.24.00237. Epub 2024 May 8.

DOI:10.1200/OP.24.00237
PMID:38718312
Abstract

In this editorial accompanying manuscript the by Klatte and colleagues, Drs Singh, and Nipp review the data behind universal germline testing in pancreatic adenocarcinoma, and review possible reasons for and solutions continued inadequate rates of germline testing in our community. Making germline testing for all patients with pancreatic adenocarcinoma is critical and will require cross-disciplinary collaboration and innovation.

摘要

在这篇伴随手稿的社论中，Klatte 博士及其同事、Singh 博士和 Nipp 博士回顾了在胰腺腺癌中进行普遍种系检测背后的数据，并回顾了我们社区中种系检测率持续不足的可能原因和解决方案。对所有胰腺腺癌患者进行种系检测至关重要，这将需要跨学科的合作和创新。

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引用本文的文献

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Cancer Susceptibility Gene Testing in Patients With Pancreatic Ductal Adenocarcinoma: Implementation in a Cancer Center Oncology Clinic.胰腺导管腺癌患者的癌症易感性基因检测：在癌症中心肿瘤诊所的实施情况
JCO Precis Oncol. 2025 Feb;9:e2400494. doi: 10.1200/PO-24-00494. Epub 2025 Feb 12.
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Hereditary Pancreatic Cancer: Advances in Genetic Testing, Early Detection Strategies, and Personalized Management.遗传性胰腺癌：基因检测、早期检测策略及个性化管理的进展
J Clin Med. 2025 Jan 9;14(2):367. doi: 10.3390/jcm14020367.