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物理治疗性脊柱侧弯特定运动对青少年特发性脊柱侧弯患者三维脊柱畸形的有效性:一项系统评价和荟萃分析。

Effectiveness of Physiotherapeutic Scoliosis-Specific Exercises on 3-Dimensional Spinal Deformities in Patients With Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis.

作者信息

You Meng-Jia, Lu Ze-Yu, Xu Qing-Yin, Chen Peng-Bo, Li Bo, Jiang Sheng-Dan, Jiang Lei-Sheng, Xia Jun, Zheng Xin-Feng

机构信息

Spine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai; Department of Medical Technology (Direction of Rehabilitation Therapy), School of Exercise and Health, Shanghai University of Sport, Shanghai, China.

Spine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai.

出版信息

Arch Phys Med Rehabil. 2024 Dec;105(12):2375-2389. doi: 10.1016/j.apmr.2024.04.011. Epub 2024 May 6.

Abstract

OBJECTIVE

To investigate the effects of physiotherapeutic scoliosis-specific exercises (PSSE) on coronal, horizontal, and sagittal deformities of the spine in adolescent idiopathic scoliosis (AIS) as well as how curve severity, intervention duration, and intervention type could modify these effects.

DATA SOURCES

Data sources included PubMed, Web of Science, Embase, Cochrane Library, and Scopus databases, which were searched from their inception to September 5, 2023.

STUDY SELECTION

Clinical controlled trials reporting the effects of PSSE on the Cobb angle, angle of trunk rotation (ATR), thoracic kyphosis (TK), or lumbar lordosis in patients with AIS aged 10-18 years. The experimental groups received PSSE; the control groups received standard care (observation or bracing) or conventional exercise such as core stabilization exercise, Pilates, proprioceptive neuromuscular facilitation, and other nonspecific exercises.

DATA EXTRACTION

Two researchers independently extracted key information from eligible studies. The quality of the studies was assessed using the Cochrane Handbook version 5.1.0 risk of bias assessment and the JBI Center for Evidence-Based Health Care (2016) of quasi-experimental research authenticity assessment tool. The level and certainty of evidence were rated according to the Grading of Recommendations, Assessment, Development, and Evaluation framework. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The protocol for this study was registered in PROSPERO (CRD42023404996).

DATA SYNTHESIS

Twelve randomized controlled trials (RCTs) and 5 non-RCTs were meta-analyzed separately. The results indicated that compared with other nonsurgical management, PSSE significantly improved the Cobb angle, ATR, and TK, whereas the lumbar lordosis improvement was not statistically significant. Additionally, the efficacy of PSSE on Cobb angle was not significant in patients with curve severity ≥30° compared with controls. Nevertheless, the pooled effect of PSSE on Cobb angle was not significantly modified by intervention duration and intervention type and that on ATR was not significantly modified by intervention duration. The overall quality of evidence according to Grading of Recommendations, Assessment, Development, and Evaluation was moderate to low for RCT and very low for non-RCT.

CONCLUSIONS

PSSE exhibited positive benefits on the Cobb angle, ATR, and TK in patients with AIS compared with other nonsurgical therapies. In addition, the effectiveness of PSSE may be independent of intervention duration and intervention type but may be influenced by the initial Cobb angle. However, more RCTs are needed in the future to validate the efficacy of PSSE in moderate AIS with a mean Cobb angle ≥30°. Current evidence is limited by inconsistent control group interventions and small sample size of the studies.

摘要

目的

探讨物理治疗性脊柱侧弯特定运动(PSSE)对青少年特发性脊柱侧弯(AIS)患者脊柱冠状面、水平面和矢状面畸形的影响,以及侧弯严重程度、干预持续时间和干预类型如何改变这些影响。

数据来源

数据来源包括PubMed、科学网、Embase、Cochrane图书馆和Scopus数据库,检索时间从建库至2023年9月5日。

研究选择

报告PSSE对10 - 18岁AIS患者Cobb角、躯干旋转角(ATR)、胸椎后凸(TK)或腰椎前凸影响的临床对照试验。试验组接受PSSE;对照组接受标准护理(观察或支具治疗)或传统运动,如核心稳定性训练、普拉提、本体感觉神经肌肉促进法及其他非特异性运动。

数据提取

两名研究人员独立从符合条件的研究中提取关键信息。采用Cochrane手册第5.1.0版偏倚风险评估和循证卫生保健JBI中心(2016年)的准实验研究真实性评估工具对研究质量进行评估。根据推荐分级、评估、制定与评价(GRADE)框架对证据水平和确定性进行评级。我们遵循系统评价和Meta分析的首选报告项目声明。本研究方案已在国际前瞻性系统评价注册库(PROSPERO,注册号:CRD42023404996)注册。

数据合成

分别对12项随机对照试验(RCT)和5项非随机对照试验进行Meta分析。结果表明,与其他非手术治疗相比,PSSE显著改善了Cobb角、ATR和TK,而腰椎前凸改善无统计学意义。此外,与对照组相比,曲线严重程度≥30°的患者中,PSSE对Cobb角的疗效不显著。然而,PSSE对Cobb角的合并效应未因干预持续时间和干预类型而显著改变,对ATR的合并效应未因干预持续时间而显著改变。根据GRADE评估,RCT证据的总体质量为中到低,非RCT证据的总体质量为极低。

结论

与其他非手术治疗相比,PSSE对AIS患者的Cobb角、ATR和TK有积极作用。此外,PSSE的有效性可能与干预持续时间和干预类型无关,但可能受初始Cobb角影响。然而,未来需要更多RCT来验证PSSE对平均Cobb角≥30°的中度AIS的疗效。目前的证据受对照组干预不一致和研究样本量小的限制。

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