Movsesian K S, Voĭtenkov B O, Mel'nikov R A, Evtiukhin A I, Stefanenko Iu F
Vopr Onkol. 1985;31(1):60-3.
The study was concerned with the immunity status of the cellular system in cancer patients and cases of chronic gastrointestinal diseases. The investigation used both standard procedure of spontaneous rosette formation and its modifications which provide indirect evidence on the status of separate subpopulations of immunocompetent cells. A reduced level of lymphocytes which form rosettes with ovine erythrocytes was found in cases of chronic diseases. Patients with gastrointestinal cancer revealed altered ratios of separate subpopulations of T-lymphocytes.
该研究关注癌症患者及慢性胃肠疾病患者细胞系统的免疫状态。调查采用了自发玫瑰花结形成的标准程序及其改进方法,这些方法为免疫活性细胞各亚群的状态提供了间接证据。在慢性疾病病例中,发现与绵羊红细胞形成玫瑰花结的淋巴细胞水平降低。胃肠癌患者显示出T淋巴细胞各亚群比例的改变。