Secretaria Municipal de Saúde de Campo Grande (SESAU), Campo Grande, MS, Brazil.
Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
AIDS Behav. 2024 Jul;28(7):2403-2409. doi: 10.1007/s10461-024-04337-8. Epub 2024 May 8.
Despite the effectiveness of antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains a global public health concern. However, weaknesses in its management regarding access to integrated HIV care include treatment gaps and loss to follow-up (LTFU) from antiretroviral treatment (ART). This study aimed to characterize the epidemiological and clinical profiles of people living with HIV/AIDS (PLHA) in LTFU from HIV care in Campo Grande, Central Brazil. This retrospective cross-sectional study was conducted between January 2021 and April 2022 using secondary data from PLHA who had LTFU in Campo Grande. A total of 852 patients with PLHA were included in this study. The majority of participants in LTFU were male (63.1%), had a CD4 cell count > 200 cells/mm (68.2%), and had been treated for ≥ 3 months (86.4%). Only 287 (33.7%) participants had undetectable HIV viral load. Of the total number of patients who returned to treatment during the study period, 448 (54.3%) were LTFU-positive. The tracking strategy was not applied to 556 (65.26%) patients, and 44.4% of the participants had been in spontaneous demand. These results highlight the relevance of patient-centered interventions and the need to ensure early treatment and promote retention in care systems with consequent viral suppression, impacting the healthcare indicators of the population, with emphasis on health managers and stakeholders in HIV care.
尽管抗逆转录病毒疗法(ART)有效,但人类免疫缺陷病毒(HIV)感染仍然是全球公共卫生关注的问题。然而,在获得综合 HIV 护理方面,其管理存在一些弱点,包括治疗差距和抗逆转录病毒治疗(ART)的失访(LTFU)。本研究旨在描述巴西中南部坎波格兰德 HIV 护理中 LTFU 的 HIV 感染者/艾滋病患者(PLHA)的流行病学和临床特征。这是一项回顾性的横断面研究,于 2021 年 1 月至 2022 年 4 月间使用在坎波格兰德 LTFU 的 PLHA 的二级数据进行。本研究共纳入 852 名 PLHA。LTFU 的大多数参与者为男性(63.1%),CD4 细胞计数>200 个细胞/mm(68.2%),且治疗时间≥3 个月(86.4%)。仅有 287 名(33.7%)参与者的 HIV 病毒载量无法检测到。在研究期间返回治疗的患者总数中,448 名(54.3%)为 LTFU 阳性。有 556 名(65.26%)患者未采用追踪策略,44.4%的参与者为自行前来。这些结果强调了以患者为中心的干预措施的重要性,需要确保早期治疗并促进在具有相应病毒抑制效果的护理系统中保持患者的治疗,这将影响人群的医疗保健指标,强调 HIV 护理的卫生管理者和利益相关者。