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硅酮支架置入治疗格雷夫斯病所致巨大甲状腺肿引起的气管狭窄:一例报告

Silicone stent placement for tracheal stenosis induced by a giant goiter due to Graves' disease: a case report.

作者信息

Misaki Mariko, Kawakita Naoya, Hara Tomoyo, Yamagami Hiroki, Takeuchi Taihei, Miyamoto Naoki, Sakamoto Shinichi, Inoue Seiya, Goto Masakazu, Toba Hiroaki, Takizawa Hiromitsu

机构信息

Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health, Biosciences, The University of Tokushima, Tokushima, Japan.

Department of Esophagus, Breast and Thyroid Surgery, Tokushima University Hospital, Tokushima, Japan.

出版信息

Gland Surg. 2024 Apr 29;13(4):578-583. doi: 10.21037/gs-23-499. Epub 2024 Apr 17.

Abstract

BACKGROUND

Although thyroid tumors with tracheal stenosis are occasionally encountered, severe tracheal stenosis caused by benign thyroid tumors is rare. We herein describe a case in which a silicone tracheal stent was placed for severe tracheal stenosis induced by a giant goiter due to Graves' disease.

CASE DESCRIPTION

A 93-year-old woman had been receiving thiamazole treatment for Graves' disease with a thyroid goiter for 32 years. She emergently presented to the hospital with sudden difficulty breathing and the temporary loss of consciousness. Although marked stridor was heard, the patient's respiratory status was stable in the first visit. Computed tomography revealed a giant thyroid goiter that extended to the mediastinum. The trachea was compressed by the sternal notch and thyroid gland, resulting in severe stenosis, and the tracheal lumen was only 1 mm. Surgical thyroidectomy was expected to be difficult due to the high risk of complications associated with the large size of the goiter and advanced age of the patient. Therefore, we decided to place a tracheal stent. A silicone stent (Dumon tube) was inserted into the site of tracheal stenosis under general anesthesia. After stent placement, respiratory distress symptoms improved, and no complications were observed. Three months after stent placement, the stent opening side was narrowed due to defective granulation and, thus, was cauterized with argon plasma coagulation.

CONCLUSIONS

We encountered a patient who was treated by tracheal silicone stent placement for severe tracheal stenosis induced by a giant goiter due to Graves' disease. A silicone stent effectively secures the airway for benign thyroid tumors that cause severe airway stenosis.

摘要

背景

虽然偶尔会遇到伴有气管狭窄的甲状腺肿瘤,但由良性甲状腺肿瘤引起的严重气管狭窄却很罕见。我们在此描述一例因格雷夫斯病导致的巨大甲状腺肿引起严重气管狭窄而置入硅胶气管支架的病例。

病例描述

一名93岁女性因格雷夫斯病合并甲状腺肿接受甲巯咪唑治疗32年。她因突发呼吸困难和短暂意识丧失紧急入院。虽然听到明显的喘鸣音,但患者首次就诊时呼吸状况稳定。计算机断层扫描显示巨大甲状腺肿延伸至纵隔。气管被胸骨切迹和甲状腺压迫,导致严重狭窄,气管腔仅1毫米。由于甲状腺肿体积大及患者年龄大,手术甲状腺切除术预计困难且并发症风险高。因此,我们决定置入气管支架。在全身麻醉下将硅胶支架(杜蒙管)插入气管狭窄部位。支架置入后,呼吸窘迫症状改善,未观察到并发症。支架置入三个月后,由于肉芽组织缺陷,支架开口侧变窄,因此用氩等离子体凝固进行烧灼。

结论

我们遇到一名因格雷夫斯病导致的巨大甲状腺肿引起严重气管狭窄而接受气管硅胶支架置入治疗的患者。硅胶支架能有效为导致严重气道狭窄的良性甲状腺肿瘤保障气道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e53b/11074657/9458af0a149c/gs-13-04-578-f1.jpg

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