Wang Jin-Xin, Li Shao-Chuan, Cai Li-Xuan, Hu Shao-Jun, Zhou Li-Peng, Yang Jian, Sun Qing-Fu
College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, People's Republic of China.
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, People's Republic of China.
Org Lett. 2024 May 17;26(19):4152-4157. doi: 10.1021/acs.orglett.4c01438. Epub 2024 May 9.
An efficient approach was developed for the synthesis of the well-known BlueCage by pre-bridging two 2,4,6-tris(4-pyridyl)-1,3,5-triazine (TPT) panels with one linker followed by cage formation in a much improved yield and shortened reaction time. Such a stepwise methodology was further applied to synthesize three new pyridinium organic cages, , , and , where the low-symmetry cages and with angled panels demonstrated better recognition properties toward 1,1'-bi-2-naphthol (BINOL) than the high-symmetry analogue featuring parallel platforms.
通过用一个连接体预桥连两个2,4,6-三(4-吡啶基)-1,3,5-三嗪(TPT)面板，然后以更高的产率和更短的反应时间形成笼状结构，开发了一种高效合成著名的BlueCage的方法。这种逐步方法进一步应用于合成三种新的吡啶鎓有机笼状物，即 、 和 ，其中具有成角度面板的低对称笼状物 和 对1,1'-联-2-萘酚(BINOL)的识别性能优于具有平行平台的高对称类似物 。
