Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Acta Neurol Belg. 2024 Aug;124(4):1155-1165. doi: 10.1007/s13760-024-02569-y. Epub 2024 May 9.
Whether in neurology or dentistry, odontogenic brain abscess stands as an ailment demanding undivided attention. The onset of this disease is insidious, with a relatively low incidence rate but a markedly high fatality rate. Moreover, its symptoms lack specificity, easily leading to misdiagnosis, oversight, and treatment delays. Hence, clinicians should maintain heightened vigilance when faced with pathogenic bacteria of dental origin in patients.
This paper encapsulates the latest research findings on the clinical manifestations and essential treatment points of odontogenic brain abscess. It may offer a crucial reference for prompt diagnosis and improved therapeutic approaches.
Odontogenic brain abscess, an infection of the cerebral parenchyma, usually appears in immunocompromised patients with dental ailments or postdental surgeries. The main pathogenic microorganisms include Streptococcus intermedius, Fusobacterium nucleatum, Streptococcus anginosus, and Millerella. Given the undetectable and nonspecific symptoms in patients, the diagnostic process relies on microbiological methods. Therefore, clinicians should actively investigate and identify the pathogenic microorganisms of odontogenic brain abscess for early detection and selection of appropriate treatment regimens to avoid disease management delays.
无论是在神经科还是牙科,牙源性脑脓肿都是一种不容忽视的疾病。这种疾病的发病隐匿,发病率相对较低,但死亡率却很高。此外,其症状缺乏特异性,容易导致误诊、漏诊和治疗延误。因此,临床医生在面对以牙源性为病因的患者时应保持高度警惕。
本文总结了牙源性脑脓肿的临床表现和基本治疗要点的最新研究结果,可为及时诊断和改善治疗方法提供重要参考。
牙源性脑脓肿是一种脑实质感染,通常发生在有牙病或牙后手术的免疫功能低下患者中。主要的病原体包括中间链球菌、核梭杆菌、咽峡链球菌和米勒链球菌。由于患者的症状无法检测且无特异性,因此诊断过程依赖于微生物学方法。因此,临床医生应积极调查和识别牙源性脑脓肿的病原体,以便早期发现并选择合适的治疗方案,避免疾病管理延误。