Graphics and Imaging Laboratory, Universitat de Girona, Girona, Catalonia.
Graphics and Imaging Laboratory, Universitat de Girona, Girona, Catalonia.
Comput Biol Med. 2024 Jun;176:108553. doi: 10.1016/j.compbiomed.2024.108553. Epub 2024 May 6.
Tissue establishments are responsible for processing, testing, preserving, storing, and distributing allografts from donors to be transplanted into recipients. In some situations, a matching process is required to determine the allograft that best fits the recipient. Allograft morphology is a key consideration for the matching process. The manual procedures applied to obtain these parameters make the process error-prone.
A new system to manage bone allograft-recipient matching for tissue establishments is proposed. The system requires bone allografts to be digitalized and the resulting images to be stored in a DICOM file. The system provides functionalities to: (i) manage DICOM files (registered in the PACs) from both allografts and recipients; (ii) reconstruct 3D models from DICOM images; (iii) explore 3D models using 2D, 3D, and multiplanar reconstructions; (iv) take allograft and recipient measurements; and (v) visualize and interact with recipient and allograft data simultaneously. The system has been installed in the Barcelona Tissue Bank (Banc de Sang i Teixits), which has digitalized the bone allografts to test the system.
A use case with a femur is presented to test all the viewer functionalities. In addition, the recipient-allograft workflow is evaluated to show the steps of the procedure where the viewer can be used.
The bone allograft-recipient matching procedure can be optimized using software tools with functionalities to visualize, interact, and take measurements.
组织机构负责处理、测试、保存、储存和分发供移植到受者体内的同种异体移植物。在某些情况下，需要匹配过程来确定最适合受者的同种异体移植物。同种异体移植物形态是匹配过程的关键考虑因素。获得这些参数的手动过程容易出错。
提出了一种用于组织机构的骨同种异体移植物-受者匹配管理的新系统。该系统要求对骨同种异体移植物进行数字化，并将生成的图像存储在 DICOM 文件中。该系统提供了以下功能：（i）管理来自同种异体移植物和受者的 DICOM 文件（在 PACs 中注册）；（ii）从 DICOM 图像重建 3D 模型；（iii）使用 2D、3D 和多平面重建探索 3D 模型；（iv）进行同种异体移植物和受者的测量；（v）可视化和同时与受者和同种异体移植物数据交互。该系统已安装在巴塞罗那组织库（血液和组织银行）中，该库已经对骨同种异体移植物进行了数字化，以测试该系统。
提出了一个股骨的用例来测试所有查看器功能。此外，还评估了受者-同种异体移植物工作流程，以显示可以使用查看器的步骤。
可以使用具有可视化、交互和测量功能的软件工具来优化骨同种异体移植物-受者匹配过程。
