Department of Urology, Duke University School of Medicine, Durham, NC.
Department of Urology, Medical University of South Carolina, Charleston, SC.
Urology. 2024 Jul;189:e1-e3. doi: 10.1016/j.urology.2024.05.002. Epub 2024 May 7.
Rhabdomyosarcoma (RMS) is among the most common pediatric solid malignancies. Fusion-negative, embryonal RMS is the predominant histology among prostate and bladder lesions. Management strategies depend on the clinical stage and risk group. Although the optimal strategy continues to evolve, the field has transitioned from radical upfront resection to organ preservation strategies with multi-modal therapy, including chemotherapy, radiation, and surgery. Survivors frequently develop late complications, including impaired fertility and sexual function, bladder dysfunction, and secondary malignancies. Our case describes an 11-year-old male who developed a radiation-induced prostatic sarcoma. We present a novel surgical technique and highlight the importance of multidisciplinary care.
横纹肌肉瘤（RMS）是最常见的儿童实体恶性肿瘤之一。融合阴性、胚胎性 RMS 是前列腺和膀胱病变中主要的组织学类型。管理策略取决于临床分期和风险组。尽管最佳策略仍在不断发展，但该领域已从激进的 upfront 切除术转变为多模式治疗的器官保留策略，包括化疗、放疗和手术。幸存者经常出现晚期并发症，包括生育和性功能受损、膀胱功能障碍和继发性恶性肿瘤。我们的病例描述了一名 11 岁男性，他患上了放射性前列腺肉瘤。我们提出了一种新的手术技术，并强调了多学科护理的重要性。
