Scott W W, Riley L H, Dorfman H D
AJR Am J Roentgenol. 1985 May;144(5):977-82. doi: 10.2214/ajr.144.5.977.
Focal lytic lesions may occur in the proximal femur associated with loosening of the femoral component of a total hip prosthesis. During long-term follow-up of 62 patients with total hip prostheses, five such lesions developed. Histologically the lesions appear to be a histiocytic response to fragmented methylmethacrylate. Radiographically the lesions may suggest infection or neoplasm. Pathologic fracture may occur through large lesions. Experience in one case suggests that thorough removal of the tissue at the time of revision may be necessary to prevent recurrence. The recent reports of several malignant neoplasms developing in association with the femoral components of total hip replacements makes recognition of these benign focal lytic lesions even more important.
局灶性溶解性病变可能出现在股骨近端，与全髋关节假体股骨部件松动相关。在对62例全髋关节假体患者的长期随访中，出现了5例此类病变。组织学上，这些病变似乎是对甲基丙烯酸甲酯碎片的组织细胞反应。影像学上，这些病变可能提示感染或肿瘤。大的病变可能会发生病理性骨折。一例病例的经验表明，翻修时彻底清除组织可能对预防复发是必要的。最近有几例与全髋关节置换股骨部件相关的恶性肿瘤的报道，这使得识别这些良性局灶性溶解性病变变得更加重要。
