Shan Divya M, Gupta Neha, Ortega-Loayza Alex G, Shea Sofia, Nandan Abhishek
School of Medicine Virginia Commonwealth University Richmond Virginia USA.
Division of Rheumatology, Allergy and Immunology Virginia Commonwealth University School of Medicine Richmond Virginia USA.
Clin Case Rep. 2024 May 8;12(5):e8884. doi: 10.1002/ccr3.8884. eCollection 2024 May.
Nuclear matrix protein (NXP-2) positive amyopathic dermatomyositis (DM) may present without classic symptoms like muscle weakness, dysphagia, and edema, and mimic conditions like cutaneous lupus. Given DM's association with malignancy and interstitial lung disease, prompt and accurate diagnosis is important. Testing for myositis-specific antibodies aids diagnosis in ambiguous cases.
核基质蛋白(NXP - 2)阳性的无肌病性皮肌炎(DM)可能不出现肌肉无力、吞咽困难和水肿等典型症状,而类似皮肤狼疮等病症。鉴于皮肌炎与恶性肿瘤和间质性肺病相关,及时准确的诊断很重要。在不明确的病例中,检测肌炎特异性抗体有助于诊断。