Okogbaa John, Batiste Lakeasha
Division of Clinical and Administrative Science, Xavier University of Louisiana, New Orleans, LA, USA.
Department of Pharmacy, West Jefferson Medical Center, Marrero, LA, USA.
Clin Med Insights Case Rep. 2019 Jun 18;12:1179547619855370. doi: 10.1177/1179547619855370. eCollection 2019.
The purpose of this case report is to assess and review the literature to determine the frequency of occurrence of dermatomyositis (DM). Dermatomyositis is a rare autoimmune condition that disproportionately affects adolescence and pediatric patients. The symptomatology experienced in this condition includes but not limited to fatigue, reduced mobility, and dysphagia. Symptoms of dysphonia and dyspnea have been reported due to weakened esophageal and respiratory muscle. Another major complication seen in DM is calcinosis. Calcinosis is a calcium deposit on soft tissue. This is mostly been attributed to late diagnosis or use of ineffective treatment regimen. Systemic corticosteroid is the first-line treatment for DM; however, other agents such as anti-malaria, IVIG, and immunosuppressive therapies have been used successfully.
本病例报告的目的是评估和回顾文献，以确定皮肌炎（DM）的发病频率。皮肌炎是一种罕见的自身免疫性疾病，对青少年和儿科患者的影响尤为严重。这种疾病所经历的症状包括但不限于疲劳、活动能力下降和吞咽困难。由于食管和呼吸肌减弱，已报告有声嘶和呼吸困难的症状。DM中另一个主要并发症是钙质沉着。钙质沉着是软组织上的钙沉积。这主要归因于诊断延迟或使用无效的治疗方案。全身性皮质类固醇是DM的一线治疗药物；然而，其他药物如抗疟疾药物、静脉注射免疫球蛋白和免疫抑制疗法也已成功使用。
