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分期腹腔镜技术治疗小儿高位腹腔内未降睾丸的比较:系统评价和荟萃分析。

Comparison between staged laparoscopic technique in children with high intra-abdominal undescended testis: a systematic review and meta-analysis.

机构信息

Urology, Padjadjaran University, Bandung, West Java, Indonesia.

出版信息

F1000Res. 2024 Apr 16;12:1511. doi: 10.12688/f1000research.141110.2. eCollection 2023.

Abstract

BACKGROUND

This study performed a systematic review and meta-analysis to compare the outcomes of the staged laparoscopic Fowler-Stephens Laparoscopic Orchiopexy (FSLO) and Staged Laparoscopic Traction Orchiopexy (SLTO) in patients with intra-abdominal testes (IAT).

METHODS

This study reviewed literature published from 2016 to 2024. A systematic literature search was conducted on three databases: PubMed, ScienceDirect, and Google Scholar, using keywords (High intra abdominal testis) AND (("Fowler Stephens laparoscopic orchiopexy" OR (FSLO)) OR (Staged Laparoscopic traction orchiopexy OR (SLTO)). Non-randomized trials and observational studies comparing staged laparoscopic FSLO and SLTO, without any time range restriction are included. Studies without FLSO orchidopexy as a control, case reports, case studies, duplicate publication, no full text and non-English studies are excluded. This study used the PRISMA protocol, the Jadad Scale, and the Newcastle Ottawa Scale (NOS) to evaluate the included studies. To analyze statistical data, the Review Manager (RevMan) software was used. The Chi-squared test was used to calculate statistical heterogeneity in the meta-analysis.

RESULTS

There were 240 patients from 5 studies (109 in the SLTO group and 131 FSLO in group). The primary outcome of this study is testicular descent and atrophy. There were no significant differences in testicular descent (RR:1.08[0.96 - 1.23],p<0.20,I :0%) and atrophy rate (RR:0.45[0.19 - 1.09],p<0.08,I :0%). Secondary outcomes are the duration of operation in both the first and second stages. Statistical analysis reveals a significantly lower first-stage operation time in the FSLO group (MD:9.31[7.08,11.55], p<0.05;I :94%). At the same time, lower second-stage operation times are significantly reported in the SLTO group (MD:-4.05[-7.99,-0.12],p<0.05; I :60%).

CONCLUSIONS

In terms of testicular descent and testicular atrophy the SLTO technique yields similar results to the FSLO technique. Both techniques have advantages and disadvantages, and we recommend SLTO as the first choice in children with a high IAT of <4 cm.

PROSPERO REGISTRATION

CRD42023412407.

摘要

背景

本研究进行了系统评价和荟萃分析,以比较分期腹腔镜 Fowler-Stephens 精索内固定术(FSLO)和分期腹腔镜牵引精索内固定术(SLTO)治疗腹腔内睾丸(IAT)患者的结局。

方法

本研究回顾了 2016 年至 2024 年发表的文献。在三个数据库:PubMed、ScienceDirect 和 Google Scholar 上使用关键词(高位腹腔睾丸)和((Fowler Stephens 腹腔镜精索固定术(FSLO))或(分期腹腔镜牵引精索固定术(SLTO))进行了系统文献检索。纳入了比较分期腹腔镜 FSLO 和 SLTO 的非随机试验和观察性研究,没有时间范围限制。排除了没有 FSLO 精索固定术作为对照、病例报告、病例研究、重复发表、无全文和非英语研究的文章。本研究使用 PRISMA 方案、Jadad 量表和纽卡斯尔-渥太华量表(NOS)来评估纳入的研究。使用 Review Manager(RevMan)软件分析统计数据。荟萃分析中使用卡方检验计算统计异质性。

结果

共有 5 项研究的 240 名患者(SLTO 组 109 例,FSLO 组 131 例)。本研究的主要结局是睾丸下降和萎缩。睾丸下降(RR:1.08[0.96-1.23],p<0.20,I²:0%)和萎缩率(RR:0.45[0.19-1.09],p<0.08,I²:0%)无显著差异。次要结局是第一阶段和第二阶段手术的持续时间。统计分析显示,FSLO 组第一阶段手术时间明显缩短(MD:9.31[7.08,11.55],p<0.05;I²:94%)。同时,SLTO 组第二阶段手术时间明显缩短(MD:-4.05[-7.99,-0.12],p<0.05;I²:60%)。

结论

在睾丸下降和睾丸萎缩方面,SLTO 技术与 FSLO 技术的结果相似。两种技术都有各自的优缺点,我们建议对于 IAT<4cm 的儿童,首选 SLTO 技术。

前瞻性注册号

CRD42023412407。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c3a/11080967/08952e73dd59/f1000research-12-164314-g0000.jpg

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