Division of Thoracic Surgery, Department of Surgery, University of Florida, Gainesville, Florida, USA.
University of Florida 1600 SW Archer Road, HD 314-B Box 100297 Gainesville, Florida 32610-0297.
Multimed Man Cardiothorac Surg. 2024 May 10;2024. doi: 10.1510/mmcts.2024.010.
A combined heart+liver transplant is the only option for survival in some patients with end-stage combined cardiac and hepatic disease. These patients may suffer from congenital or acquired cardiac disease. The potential aetiologies of the associated hepatic disease are heterogeneous and include systemic disease that impacts the liver as well as venous congestion in patients with functionally univentricular circulation. In the latter scenario, patients with functionally univentricular circulation often require complex cardiac reconstruction in the setting of a cardiac transplant after staged palliation. During cardiac procurement, our approach is to dissect the entire ascending aorta and aortic arch in continuity; the entire superior caval vein and innominate vein in continuity; and the pulmonary arteries from hilum to hilum if the donor is not a candidate for recovery of the lungs. The cardiac and abdominal organ procurement teams work in parallel during dissection and combined en bloc cardio-hepatectomy. This technique minimizes exposure of both organs to cold ischaemia. This video tutorial demonstrates the key steps for combined en bloc heart+liver organ procurement.
在一些患有终末期心脏和肝脏联合疾病的患者中,心脏+肝脏联合移植是唯一的生存选择。这些患者可能患有先天性或后天性心脏病。相关肝脏疾病的潜在病因多种多样,包括影响肝脏的全身性疾病以及功能单心室循环患者的静脉充血。在后一种情况下,功能单心室循环的患者通常需要在心脏移植后进行分期姑息治疗时进行复杂的心脏重建。在心脏获取过程中,我们的方法是连续解剖整个升主动脉和主动脉弓;连续解剖整个上腔静脉和无名静脉;如果供体不适合恢复肺部,则从肺门到肺门解剖肺动脉。在解剖过程中,心脏和腹部器官获取团队并行工作,并进行联合整块心-肝切除术。该技术可将两个器官暴露于低温缺血的时间最小化。本视频教程演示了联合整块心-肝器官获取的关键步骤。