印度 1993-2021 年的新生儿期、晚期新生儿期、后期新生儿期和儿童死亡率。
Early-Neonatal, Late-Neonatal, Postneonatal, and Child Mortality Rates Across India, 1993-2021.
机构信息
Harvard Center for Population and Development Studies, Boston, Massachusetts.
Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
出版信息
JAMA Netw Open. 2024 May 1;7(5):e2410046. doi: 10.1001/jamanetworkopen.2024.10046.
IMPORTANCE
The global success of the child survival agenda depends on how rapidly mortality at early ages after birth declines in India, and changes need to be monitored to evaluate the status.
OBJECTIVE
To understand the disaggregated patterns of decrease in early-life mortality across states and union territories (UTs) of India.
DESIGN, SETTING, AND PARTICIPANTS: Repeated cross-sectional data from the 5 rounds of the National Family Health Survey conducted in 1992-1993, 1998-1999, 2005-2006, 2015-2016, and 2019-2021 were used in a representative population-based study. The study was based on data of children born in the past 5 years with complete information on date of birth and age at death. The analysis was conducted in February 2024.
EXPOSURE
Time and geographic units.
MAIN OUTCOMES AND MEASURES
Mortality rates were computed for 4 early-life periods: early-neonatal (first 7 days), late-neonatal (8-28 days), postneonatal (29 days to 11 months), and child (12-59 months). For early and late neonatal periods, the rates are expressed as deaths per 1000 live births, for postneonatal, as deaths per 1000 children aged at least 29 days and for child, deaths per 1000 children aged at least 1 year. These are collectively mentioned as deaths per 1000 for all mortalities. The relative burden of each of the age-specific mortalities to total mortality in children younger than 5 years was also computed.
RESULTS
The final analytical sample included 33 667 (1993), 29 549 (1999), 23 020 (2006), 82 294 (2016), and 64 242 (2021) children who died before their fifth birthday in the past 5 years of each survey. Mortality rates were lowest for the late-neonatal and child periods; early-neonatal was the highest in 2021. Child mortality experienced the most substantial decrease between 1993 and 2021, from 33.5 to 6.9 deaths per 1000, accompanied by a substantial reduction in interstate inequalities. While early-neonatal (from 33.5 to 20.3 deaths per 1000), late-neonatal (from 14.1 to 4.1 deaths per 1000), and postneonatal (from 31.0 to 10.8 deaths per 1000) mortality also decreased, interstate inequalities remained notable. The mortality burden shifted over time and is now concentrated during the early-neonatal (48.3% of total deaths in children younger than 5 years) and postneonatal (25.6%) periods. A stagnation or worsening for certain states and UTs was observed from 2016 to 2021 for early-neonatal, late-neonatal, and postneonatal mortality. If this pattern continues, these states and UTs will not meet the United Nations Sustainable Development Goal targets related to child survival.
CONCLUSIONS AND RELEVANCE
In this repeated cross-sectional study of 5 time periods, the decrease in mortality during early-neonatal and postneonatal phases of mortality was relatively slower, with notable variations across states and UTs. The findings suggest that policies pertaining to early-neonatal and postneonatal mortalities need to be prioritized and targeting of policies and interventions needs to be context-specific.
重要性
全球儿童生存议程的成功取决于印度出生后早期死亡率下降的速度有多快,需要监测变化以评估现状。
目的
了解印度各州和联邦属地(UT)之间早期生命死亡率下降的细分模式。
设计、地点和参与者:使用了 1992-1993 年、1998-1999 年、2005-2006 年、2015-2016 年和 2019-2021 年五次全国家庭健康调查的重复横断面数据进行了一项代表性的基于人群的研究。该研究基于过去 5 年出生的儿童的数据,这些儿童的出生日期和死亡时的年龄信息完整。分析于 2024 年 2 月进行。
暴露
时间和地理单位。
主要结果和测量
计算了 4 个早期生命时期的死亡率:早期新生儿期(出生后前 7 天)、晚期新生儿期(第 8-28 天)、后期新生儿期(出生后 29 天至 11 个月)和儿童期(12-59 个月)。对于早期和晚期新生儿期,死亡率表示为每 1000 例活产中的死亡人数,对于后期新生儿期,死亡率表示为每 1000 名至少 29 天大的儿童中的死亡人数,对于儿童期,死亡率表示为每 1000 名至少 1 岁的儿童中的死亡人数。这些死亡率统称为所有死亡人数的每 1000 人。还计算了每个年龄特定死亡率相对于 5 岁以下儿童总死亡率的相对负担。
结果
最终分析样本包括 33667(1993 年)、29549(1999 年)、23020(2006 年)、82294(2016 年)和 64242(2021 年)名在过去 5 年的每个调查中,在五岁生日前死亡的儿童。晚期新生儿期和儿童期的死亡率最低;2021 年早期新生儿期的死亡率最高。自 1993 年至 2021 年,儿童死亡率下降幅度最大,从每 1000 人 33.5 人降至 6.9 人,州际不平等现象也大幅减少。虽然早期新生儿期(从每 1000 人 33.5 人降至 20.3 人)、晚期新生儿期(从每 1000 人 14.1 人降至 4.1 人)和后期新生儿期(从每 1000 人 31.0 人降至 10.8 人)的死亡率也有所下降,但州际不平等仍然很明显。死亡率负担随时间转移,现在集中在早期新生儿期(5 岁以下儿童总死亡人数的 48.3%)和后期新生儿期(25.6%)。从 2016 年到 2021 年,某些州和 UT 出现了早期新生儿期、晚期新生儿期和后期新生儿期死亡率停滞或恶化的情况。如果这种模式继续下去,这些州和 UT 将无法实现与儿童生存有关的联合国可持续发展目标。
结论和相关性
在这项 5 个时期的重复横断面研究中,早期新生儿期和后期新生儿期死亡率的下降相对较慢,各州和 UT 之间存在显著差异。研究结果表明,需要优先考虑早期新生儿期和后期新生儿期的死亡率政策,并针对具体情况制定政策和干预措施。