Kirklin J W, Kouchoukos N T, Blackstone E H, Oberman A
Circulation. 1979 Dec;60(7):1613-8. doi: 10.1161/01.cir.60.7.1613.
In the past 20 years, basic and clinical research have provided new information on coronary artery surgery. For example, several studies have shown that coronary artery bypass grafting is more effective than medical treatment in relieving the symptoms of chronic disabling angina pectoris. However, we still do not have definitive answers to many questions. What factors in the patient, in the operation and in the care after operation determine success in surgical treatment? Does the operation prolong useful life? Is the operation affordable? These questions are difficult. Further research is needed to solve complex problems relating to surgical vs medical treatment of coronary artery disease.
在过去20年里,基础研究和临床研究为冠状动脉手术提供了新的信息。例如,多项研究表明,冠状动脉旁路移植术在缓解慢性致残性心绞痛症状方面比药物治疗更有效。然而,对于许多问题我们仍然没有确切的答案。患者自身因素、手术过程以及术后护理中的哪些因素决定了手术治疗的成功?手术能延长有益的生命吗?手术费用是否可承受?这些问题都很棘手。需要进一步的研究来解决与冠状动脉疾病手术治疗和药物治疗相关的复杂问题。