School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, No.5 Sassoon Road, Pokfulam, Hong Kong SAR, China.
Department of Neurosurgery, Gansu Provincial Maternity and Child Care Hospital, No.999 Mogao Avenue, Lanzhou, Gansu, China.
J Health Popul Nutr. 2024 May 10;43(1):62. doi: 10.1186/s41043-024-00561-z.
Seasonal influenza causes annual school breaks and student absenteeism in Hong Kong schools and kindergartens. This proposal aims to conduct a retrospective cohort study to evaluate the impact of a school-based influenza vaccination (SIV) programme on absenteeism and outbreaks at schools in Hong Kong.
The study will compare schools that implemented the SIV programme with schools that did not. The data will be sourced from school records, encompassing absenteeism records, outbreak reports, and vaccination rates. We will recruit 1000 students from 381 schools and kindergartens in 18 districts of Hong Kong starting June 2024. The primary outcome measures will include absenteeism rates due to influenza and school influenza outbreaks. Secondary outcomes will consist of vaccination coverage rates and the impact of the SIV programme on hospitalisations due to influenza-like illness. A t-test will be conducted to compare the outcomes between schools with and without the SIV programme.
The school completed signing the participants' informed consent form before reporting the data to us. Our study has been approved by the Hospital Authority Hong Kong West Cluster IRB Committee (IRB No: UW 17-111) and was a subtopic of the research "The estimated age-group specific influenza vaccine coverage rates in Hong Kong and the impact of the school outreach vaccination program".
This study will be retrospectively registered.
季节性流感会导致香港学校和幼儿园每年停课和学生缺勤。本研究旨在进行回顾性队列研究，以评估基于学校的流感疫苗接种（SIV）计划对香港学校缺勤和疫情爆发的影响。
本研究将比较实施 SIV 计划的学校和未实施的学校。数据将来自学校记录，包括缺勤记录、疫情报告和疫苗接种率。我们将于 2024 年 6 月从香港 18 个区的 381 所学校和幼儿园招募 1000 名学生。主要结局指标将包括因流感导致的缺勤率和学校流感疫情爆发。次要结局指标将包括疫苗接种覆盖率和 SIV 计划对因流感样疾病住院的影响。将采用 t 检验比较有和没有 SIV 计划的学校的结果。
学校在向我们报告数据之前已完成签署参与者的知情同意书。我们的研究已获得香港医管局西联网服务伦理委员会（IRB 编号：UW 17-111）的批准，也是研究“香港特定年龄组流感疫苗覆盖率估计数及其对学校外展疫苗接种计划的影响”的子课题。
本研究将进行回顾性注册。
