Yano Tomonori, Yamamoto Hironori
Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke 329-0498, Japan.
Cancers (Basel). 2024 Apr 27;16(9):1704. doi: 10.3390/cancers16091704.
Recent technological advances, including capsule endoscopy (CE) and balloon-assisted endoscopy (BAE), have revealed that small intestinal disease is more common than previously thought. CE has advantages, including a high diagnostic yield, discomfort-free, outpatient basis, and physiological images. BAE enabled endoscopic diagnosis and treatment in the deep small bowel. Computed tomography (CT) enterography with negative oral contrast can evaluate masses, wall thickening, and narrowing of the small intestine. In addition, enhanced CT can detect abnormalities outside the gastrointestinal tract that endoscopy cannot evaluate. Each modality has its advantages and disadvantages, and a good combination of multiple modalities leads to an accurate diagnosis. As a first-line modality, three-phase enhanced CT is preferred. If CT shows a mass, stenosis, or wall thickening, a BAE should be selected. If there are no abnormal findings on CT and no obstructive symptoms, CE should be selected. If there are significant findings in the CE, determine the indication for BAE and its insertion route based on these findings. Early diagnosis of small intestinal tumors is essential for favorable outcomes. For early diagnosis, the possibility of small bowel lesions should be considered in patients with unexplained symptoms and signs after examination of the upper and lower gastrointestinal tract.
包括胶囊内镜(CE)和气囊辅助内镜(BAE)在内的近期技术进展表明,小肠疾病比之前认为的更为常见。胶囊内镜具有诸多优势,包括高诊断率、无不适感、门诊操作以及可获取生理图像。气囊辅助内镜能够对深部小肠进行内镜诊断和治疗。口服阴性对比剂的计算机断层扫描(CT)小肠造影可评估小肠的肿物、肠壁增厚及狭窄情况。此外,增强CT能够检测出内镜无法评估的胃肠道外异常。每种检查方式都有其优缺点,多种检查方式的良好结合有助于准确诊断。作为一线检查方式,首选三相增强CT。如果CT显示有肿物、狭窄或肠壁增厚,应选择气囊辅助内镜检查。如果CT未发现异常且无梗阻症状,则应选择胶囊内镜检查。如果胶囊内镜检查有重要发现,应根据这些发现确定气囊辅助内镜检查的适应证及其插入途径。小肠肿瘤的早期诊断对于取得良好预后至关重要。为实现早期诊断,对于经上、下消化道检查后仍有无法解释的症状和体征的患者,应考虑小肠病变的可能性。