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妊娠期贫血

Anaemia of pregnancy.

作者信息

Mayet F G

出版信息

S Afr Med J. 1985 May 17;67(20):804-9.

PMID:3873115
Abstract

This paper reports the findings of a cross-sectional study of anaemia in Indian and black women attending an antenatal clinic. Anaemia as defined by current World Health Organization criteria was detected in 13,2% of Indian women in the first trimester of pregnancy, in 28,1% in the second trimester and in 47,0% in the third trimester. Iron deficiency, diagnosed on the basis of low serum ferritin levels (less than 12 ng/ml), was common, the prevalence being 35% in the first trimester and rising to 86% in the third; this demonstrates the effects of the progressively increasing stress on iron metabolism as pregnancy advances. Reduced folate levels (less than 3 ng/ml) were detected in 8,8% of subjects in the first trimester and in 47% in the third. It may therefore be concluded that anaemia was common in this group and that its prevalence increased progressively as pregnancy advanced. Iron deficiency was by far the commonest type of deficiency observed. While folate levels were low in a fair proportion of subjects, evidence of coexistent iron deficiency was found in all of them. It is therefore not clear whether or not a primary nutritional deficiency of folic acid contributed towards the production of anaemia. A similar study was done among pregnant black women. Anaemia was detected in 18,8%, 26,0% and 28,6% of subjects in the three trimesters. Iron deficiency, diagnosed on the basis of low serum ferritin levels, was observed in 19% and 40% of women in the first and third trimesters respectively. Reduced folate levels were found in 8,7% of subjects in the first trimester and in 10% in the third.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本文报告了一项针对在产前诊所就诊的印度和黑人女性贫血情况的横断面研究结果。根据世界卫生组织现行标准定义的贫血,在印度女性中,孕早期的检出率为13.2%,孕中期为28.1%,孕晚期为47.0%。基于低血清铁蛋白水平(低于12 ng/ml)诊断出的缺铁情况很常见,孕早期患病率为35%,到孕晚期升至86%;这表明随着孕期推进,铁代谢所承受的压力逐渐增加。孕早期8.8%的受试者和孕晚期47%的受试者叶酸水平降低(低于3 ng/ml)。因此可以得出结论,该群体中贫血情况常见,且患病率随孕期推进而逐渐上升。缺铁是迄今观察到的最常见的缺乏类型。虽然相当一部分受试者叶酸水平较低,但在所有受试者中都发现了同时存在缺铁的证据。因此,尚不清楚叶酸原发性营养缺乏是否导致了贫血。对怀孕黑人女性进行了类似研究。三个孕期中受试者贫血的检出率分别为18.8%、26.0%和28.6%。基于低血清铁蛋白水平诊断出的缺铁情况,在孕早期和孕晚期的女性中分别观察到19%和40%。孕早期8.7%的受试者和孕晚期10%的受试者叶酸水平降低。(摘要截选至250词)

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