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食物过敏的病程、诊断和治疗的差异取决于年龄——儿童与成人的比较。

Differences in the Course, Diagnosis, and Treatment of Food Allergies Depending on Age-Comparison of Children and Adults.

机构信息

Student Scientific Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-369 Wroclaw, Poland.

Department of Internal Medicine, Pneumology and Allergology, Wroclaw Medical University, 50-369 Wroclaw, Poland.

出版信息

Nutrients. 2024 Apr 27;16(9):1317. doi: 10.3390/nu16091317.

Abstract

Food allergy (FA) has become a common global public health issue, with a growing prevalence in the modern world and a significant impact on the lives of patients, their families, and caregivers. It affects every area of life and is associated with elevated costs. Food allergy is an adverse immune reaction that occurs in response to a given food. The symptoms vary from mild to severe and can lead to anaphylaxis. This is why it is important to focus on the factors influencing the occurrence of food allergies, specific diagnostic methods, effective therapies, and especially prevention. Recently, many guidelines have emphasized the impact of introducing specific foods into a child's diet at an early age in order to prevent food allergies. Childhood allergies vary with age. In infants, the most common allergy is to cow's milk. Later in life, peanut allergy is more frequently diagnosed. Numerous common childhood allergies can be outgrown by adulthood. Adults can also develop new IgE-mediated FA. The gold standard for diagnosis is the oral provocation test. Skin prick tests, specific IgE measurements, and component-resolved diagnostic techniques are helpful in the diagnosis. Multiple different approaches are being tried as possible treatments, such as immunotherapy or monoclonal antibodies. This article focuses on the prevention and quality of life of allergic patients. This article aims to systematize the latest knowledge and highlight the differences between food allergies in pediatric and adult populations.

摘要

食物过敏(FA)已成为一个常见的全球公共卫生问题,在现代世界中患病率不断上升,对患者、他们的家人和照顾者的生活产生重大影响。它影响生活的各个方面,并与成本升高有关。食物过敏是一种针对特定食物的免疫不良反应。症状从轻微到严重不等,可能导致过敏反应。这就是为什么要关注影响食物过敏发生的因素、特定的诊断方法、有效的治疗方法,尤其是预防措施非常重要的原因。最近,许多指南强调了在儿童早期引入特定食物到饮食中的重要性,以预防食物过敏。儿童时期的过敏与年龄有关。在婴儿中,最常见的过敏是对牛奶的过敏。随着年龄的增长,花生过敏更为常见。许多常见的儿童期过敏可以在成年后自行消退。成年人也可能会产生新的 IgE 介导的 FA。诊断的金标准是口服激发试验。皮肤点刺试验、特异性 IgE 测量和成分解析诊断技术有助于诊断。正在尝试多种不同的方法作为可能的治疗方法,例如免疫疗法或单克隆抗体。本文重点介绍过敏患者的预防和生活质量。本文旨在系统地总结最新知识,并突出儿科和成人人群中食物过敏之间的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc5/11085589/33f36fcb106b/nutrients-16-01317-g001.jpg

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