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机器学习技术在预测自身免疫性风湿病合并妊娠中的应用及挑战。

Machine learning techniques for prediction in pregnancy complicated by autoimmune rheumatic diseases: Applications and challenges.

机构信息

Department of Pharmacy, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Department of Pharmacy, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.

出版信息

Int Immunopharmacol. 2024 Jun 15;134:112238. doi: 10.1016/j.intimp.2024.112238. Epub 2024 May 11.

Abstract

Autoimmune rheumatic diseases are chronic conditions affecting multiple systems and often occurring in young women of childbearing age. The diseases and the physiological characteristics of pregnancy significantly impact maternal-fetal health and pregnancy outcomes. Currently, the integration of big data with healthcare has led to the increasing popularity of using machine learning (ML) to mine clinical data for studying pregnancy complications. In this review, we introduce the basics of ML and the recent advances and trends of ML in different prediction applications for common pregnancy complications by autoimmune rheumatic diseases. Finally, the challenges and future for enhancing the accuracy, reliability, and clinical applicability of ML in prediction have been discussed. This review will provide insights into the utilization of ML in identifying and assisting clinical decision-making for pregnancy complications, while also establishing a foundation for exploring comprehensive management strategies for pregnancy and enhancing maternal and child health.

摘要

自身免疫性风湿病是影响多个系统的慢性疾病,常发生在生育年龄的年轻女性中。这些疾病和妊娠的生理特征显著影响母婴健康和妊娠结局。目前,大数据与医疗保健的融合使得使用机器学习 (ML) 挖掘临床数据来研究妊娠并发症的应用越来越广泛。在这篇综述中,我们介绍了 ML 的基础知识,以及 ML 在不同预测应用中的最新进展和趋势,用于预测自身免疫性风湿病相关的常见妊娠并发症。最后,讨论了提高 ML 在预测中的准确性、可靠性和临床适用性的挑战和未来方向。这篇综述将为 ML 在识别和协助妊娠并发症的临床决策方面的应用提供思路,同时也为探索妊娠的综合管理策略和提高母婴健康奠定基础。

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