Department of Neuromicrobiology, NIMHANS, Bengaluru, 29, India.
Department of Neurosurgery, NIMHANS, Bengaluru, 29, India.
Indian J Med Microbiol. 2024 May-Jun;49:100609. doi: 10.1016/j.ijmmb.2024.100609. Epub 2024 May 19.
We discuss a rare instance of cryptococcoma caused by Cryptococcus gattii in a 55-year-old woman initially treated for suspected COVID bronchopneumonia. The diagnosis posed a challenge due to vague symptoms and unclear imaging findings suggesting malignancy. Postoperative samples confirmed the presence of Cryptococcus gattii through culture of brain tissue and blood. Appropriate therapy was initiated, but despite treatment, it led to a fatal outcome. The case emphasizes the crucial role of microbiologist in early diagnosis of fungal infections of Central Nervous System. Additionally, the delayed diagnosis in immunocompetent individuals highlights the critical need for early recognition and intervention to mitigate potentially fatal outcomes.
我们讨论了一例由新型隐球菌引起的隐球菌瘤的罕见病例,该病例发生在一名 55 岁女性身上,最初被怀疑患有 COVID 支气管肺炎。由于症状模糊且影像学检查结果不明确提示恶性肿瘤,因此该诊断极具挑战性。术后样本通过脑组织和血液的培养确认了新型隐球菌的存在。尽管进行了适当的治疗,但还是导致了致命的后果。该病例强调了微生物学家在中枢神经系统真菌感染早期诊断中的关键作用。此外,免疫功能正常的个体中存在延迟诊断的情况,这突出表明迫切需要早期识别和干预,以减轻可能致命的后果。