Kitaura Tsuyoshi, Takahashi Masamichi, Umeyama Takashi, Takeshita Nozomi, Katanami Yuichi, Takaya Saho, Yamamoto Kei, Kutsuna Satoshi, Hayakawa Kayoko, Kato Yasuyuki, Yamauchi Takahiro, Narita Yoshitaka, Miyazaki Yoshitsugu, Ohmagari Norio
Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
J Infect Chemother. 2018 Jul;24(7):573-575. doi: 10.1016/j.jiac.2017.12.014. Epub 2018 Jan 17.
A 71-year-old Japanese man with travel history to the Vancouver Island, Canada was diagnosed the pulmonary and central nervous system infections caused by Cryptococcus gattii genotype VGIIa. This is the first imported case of Cryptococcus gattii genotype VGIIa infection from endemic area of North America to Japan. He was recovery with no residual neurological dysfunction by early resection of brain mass and antifungal therapy. Early surgical resection of cerebellar cryptococcoma may shorten the length of induction therapy with antifungal drugs.
一名有加拿大温哥华岛旅行史的71岁日本男性被诊断为由加氏隐球菌VGIIa基因型引起的肺部和中枢神经系统感染。这是北美疫区加氏隐球菌VGIIa基因型感染输入日本的首例病例。通过早期切除脑肿块和抗真菌治疗，他康复且无残留神经功能障碍。早期手术切除小脑隐球菌瘤可能会缩短抗真菌药物诱导治疗的疗程。
