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一名年轻成年人的椎动脉夹层:病例报告

Vertebral Artery Dissection in a Young Adult: A Case Report.

作者信息

Toluie Ava, Joseph Anthony T, Hrehorovich Peter A

机构信息

Pediatrics, Lake Erie College of Osteopathic Medicine, Bradenton, USA.

Orthopedic Surgery, Lake Erie College of Osteopathic Medicine, Bradenton, USA.

出版信息

Cureus. 2024 Apr 12;16(4):e58100. doi: 10.7759/cureus.58100. eCollection 2024 Apr.

DOI:10.7759/cureus.58100
PMID:38738014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11088753/
Abstract

Vertebral artery dissections (VAD) pose a significant risk for strokes, particularly in young adults. This case report details the presentation and management of a 48-year-old patient who was diagnosed with an extracranial VAD following cervical spine manipulation (CSM). The patient's symptoms included acute right-sided ataxia, giddiness, vertigo, nausea, vomiting, and persistent pain behind the right ear, prompting immediate evaluation. After ruling out acute intracerebral hemorrhages, a computed tomography angiogram (CTA) of the head and neck identified a severe narrowing of the right distal vertebral artery with a string sign at the level of the right C1 loop (V3 segment), indicating an extracranial VAD. This finding was further supported when ultrasound (US) imaging revealed a high resistance flow pattern in the right distal vertebral artery. Furthermore, T2 and diffusion-weighted magnetic resonance imaging (MRI) confirmed a 1.8 cm VAD/hematoma and a 1.4 cm acute/subacute infarct in the right posterior inferior cerebellar artery (PICA) territory. This research accentuates the importance of recognizing and addressing that neck pain can be a symptom of musculoskeletal dysfunction or could have neurovascular origins. In this case, the patient's neck pain may have been musculoskeletal or could have been due to a previous dissection. Thus, differentiation should be considered before cervical spine manipulation.

摘要

椎动脉夹层(VAD)会给中风带来重大风险,尤其是在年轻人中。本病例报告详细介绍了一名48岁患者的临床表现及治疗情况,该患者在接受颈椎推拿(CSM)后被诊断为颅外VAD。患者的症状包括急性右侧共济失调、头晕、眩晕、恶心、呕吐以及右耳后持续疼痛,促使其立即接受评估。在排除急性脑出血后,对头颈部进行的计算机断层血管造影(CTA)显示右侧椎动脉远端严重狭窄,在右侧C1袢(V3段)水平出现线样征,提示颅外VAD。超声(US)成像显示右侧椎动脉远端血流呈高阻力型,进一步支持了这一发现。此外,T2加权和弥散加权磁共振成像(MRI)证实右侧小脑后下动脉(PICA)区域存在1.8 cm的VAD/血肿以及1.4 cm的急性/亚急性梗死。本研究强调了认识到颈部疼痛可能是肌肉骨骼功能障碍的症状或可能源于神经血管问题并加以处理的重要性。在本病例中,患者的颈部疼痛可能是肌肉骨骼性的,也可能是由于先前的夹层所致。因此,在进行颈椎推拿之前应考虑进行鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/b9633cda2174/cureus-0016-00000058100-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/7d56afaecadd/cureus-0016-00000058100-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/cb9025ba0dc8/cureus-0016-00000058100-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/9965d686e1ed/cureus-0016-00000058100-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/321b04bc1f22/cureus-0016-00000058100-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/b9633cda2174/cureus-0016-00000058100-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/7d56afaecadd/cureus-0016-00000058100-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/cb9025ba0dc8/cureus-0016-00000058100-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/9965d686e1ed/cureus-0016-00000058100-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/321b04bc1f22/cureus-0016-00000058100-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4573/11088753/b9633cda2174/cureus-0016-00000058100-i05.jpg

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本文引用的文献

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Vertebral artery dissection induced lateral medullary syndrome characterized with severe bradycardia: a case report and review of the literature.椎动脉夹层所致延髓外侧综合征伴严重心动过缓:病例报告及文献复习。
Ann Palliat Med. 2022 Oct;11(10):3330-3336. doi: 10.21037/apm-22-1098.
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Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.抗血小板治疗与抗凝治疗在颈动脉夹层中的应用:中风研究中的颈动脉夹层(CADISS)随机临床试验最终结果。
JAMA Neurol. 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072.
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Extracranial and intracranial vertebral artery dissections: A comparison of clinical findings.
颅外和颅内椎动脉夹层:临床发现的比较。
J Neurol Sci. 2016 Mar 15;362:244-50. doi: 10.1016/j.jns.2016.01.062. Epub 2016 Jan 29.
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Comparison of potential risks between intracranial and extracranial vertebral artery dissections.颅内与颅外椎动脉夹层潜在风险的比较。
Eur Neurol. 2014;71(5-6):305-12. doi: 10.1159/000357867. Epub 2014 Mar 21.
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