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黄疸与降钙素原水平升高揭示一例伴胰腺转移的小细胞肺癌：来自摩洛哥东部的病例报告

Jaundice and Higher Procalcitonin Level Revealing a Small-Cell Lung Cancer With Pancreatic Metastasis: A Case Report From Eastern Morocco.

作者信息

Chibani Hind, El Ouardani Soufia, Omari Mouhsine, Nassira Karich, Al Jarroudi Ouissam, Hadj Kacem Hanane, Brahmi Sami Aziz, Bennani Amal, Afqir Said

机构信息

Medical Oncology, Mohammed VI University Hospital, Oujda, MAR.

Medical Oncology, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.

出版信息

Cureus. 2024 Apr 11;16(4):e58041. doi: 10.7759/cureus.58041. eCollection 2024 Apr.

DOI:10.7759/cureus.58041
PMID:38738076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11088360/
Abstract

Small-cell lung cancer (SCLC) is highly aggressive, with a severe tendency for metastasis. Pancreatic metastasis in SCLC is uncommon, also jaundice as a major symptom of small-cell lung cancer is even rarer. The diagnosis of pancreatic metastasis is a real challenge for the medical team, it relies on both radiological and pathological details. We report a case of a 58-year-old male admitted for SCLC with pancreatic metastasis and a higher level of procalcitonin. He received platinum-based chemotherapy with a swell response. The focus of this study will be on the characteristics of pancreatic metastasis, along with their diagnosis and treatment approaches. Procalcitonin as a paraneoplastic syndrome will also be discussed in this study.

摘要

小细胞肺癌（SCLC）具有高度侵袭性，有严重的转移倾向。SCLC发生胰腺转移并不常见，而黄疸作为小细胞肺癌的主要症状则更为罕见。胰腺转移的诊断对医疗团队来说是一项真正的挑战，它依赖于放射学和病理学细节。我们报告一例58岁男性因小细胞肺癌伴胰腺转移及降钙素原水平升高入院。他接受了铂类化疗，反应良好。本研究的重点将是胰腺转移的特征及其诊断和治疗方法。本研究还将讨论降钙素原作为一种副肿瘤综合征的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/a7001d1df50d/cureus-0016-00000058041-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/0f795762965f/cureus-0016-00000058041-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/d59664b92e58/cureus-0016-00000058041-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/52a5c5d8e38e/cureus-0016-00000058041-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/a7001d1df50d/cureus-0016-00000058041-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/0f795762965f/cureus-0016-00000058041-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/d59664b92e58/cureus-0016-00000058041-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/52a5c5d8e38e/cureus-0016-00000058041-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7826/11088360/a7001d1df50d/cureus-0016-00000058041-i04.jpg

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本文引用的文献

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Small Cell Lung Carcinoma: Current Diagnosis, Biomarkers, and Treatment Options with Future Perspectives.小细胞肺癌：当前诊断、生物标志物及治疗选择与未来展望
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