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双侧神经节囊区及左侧丘脑微血管病变患者的Parinaud综合征

Parinaud Syndrome in a Patient With Microangiopathic Lesions in the Bilateral Gangliocapsular Region and Left Thalamus.

作者信息

Magdum Renu, Aher Priyanka S

机构信息

Ophthalmology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND.

出版信息

Cureus. 2024 Apr 12;16(4):e58120. doi: 10.7759/cureus.58120. eCollection 2024 Apr.

DOI:10.7759/cureus.58120
PMID:38738087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11088869/
Abstract

Parinaud syndrome, which most commonly involves the dorsal midbrain, has classical features of upward gaze paralysis, convergence-retraction nystagmus, and pupillary light near dissociation. A 62-year-old male presented to the Eye department with diminution of vision and symptoms of dry eye with associated difficulty in walking. Examination revealed nystagmus while performing convergence test. An MRI revealed lesions in the thalamic and gangliocapsular regions. Microangiopathies involving the thalamus and gangliocapsular region can lead to Parinaud syndrome. In our case, microangiopathies were most probably hypertensive.

摘要

帕里诺综合征最常累及中脑背侧，具有向上凝视麻痹、集合-回缩性眼球震颤和瞳孔光近反射分离等典型特征。一名62岁男性因视力减退、干眼症状及行走困难就诊于眼科。检查发现进行集合试验时出现眼球震颤。磁共振成像显示丘脑和神经节囊区域有病变。累及丘脑和神经节囊区域的微血管病变可导致帕里诺综合征。在我们的病例中，微血管病变很可能是高血压性的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/185e62806bf6/cureus-0016-00000058120-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/6881a51dacfa/cureus-0016-00000058120-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/e93d64dbb210/cureus-0016-00000058120-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/185e62806bf6/cureus-0016-00000058120-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/6881a51dacfa/cureus-0016-00000058120-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/e93d64dbb210/cureus-0016-00000058120-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8157/11088869/185e62806bf6/cureus-0016-00000058120-i03.jpg

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Parinaud Syndrome in a Patient With Microangiopathic Lesions in the Bilateral Gangliocapsular Region and Left Thalamus.双侧神经节囊区及左侧丘脑微血管病变患者的Parinaud综合征
Cureus. 2024 Apr 12;16(4):e58120. doi: 10.7759/cureus.58120. eCollection 2024 Apr.
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本文引用的文献

1
Parinaud syndrome: a 25-year (1991-2016) review of 40 consecutive adult cases.帕里诺综合征：对40例连续成年病例的25年（1991 - 2016年）回顾
Acta Ophthalmol. 2017 Dec;95(8):e792-e793. doi: 10.1111/aos.13283. Epub 2016 Oct 24.
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Parinaud's syndrome in a patient with thalamic infarction due to cerebral venous thrombosis.
Indian J Ophthalmol. 2007 May-Jun;55(3):237-8. doi: 10.4103/0301-4738.31954.
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Reverse Parinaud's syndrome due to pineal tumour.
Indian J Ophthalmol. 1995 Mar;43(1):31-2.
4
Paralysis of down-gaze.下视麻痹。
Arch Ophthalmol. 1974 Mar;91(3):192-9. doi: 10.1001/archopht.1974.03900060200009.
5
The lesions producing paralysis of downward but not upward gaze.这些病变导致向下注视麻痹但不导致向上注视麻痹。
Arch Neurol. 1973 May;28(5):319-23. doi: 10.1001/archneur.1973.00490230055007.